ACTH (1-39) (mouse, rat)

ACTH (1-39) (mouse, rat) Structure
ACTH (1-39) (mouse, rat) structure
Common Name ACTH (1-39) (mouse, rat)
CAS Number 77465-10-2 Molecular Weight 4582.23
Density N/A Boiling Point N/A
Molecular Formula C210H315N57O57S Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning

Endogenous ACTH, not only alpha-melanocyte-stimulating hormone, reduces food intake mediated by hypothalamic mechanisms.

Am. J. Physiol. Cell Physiol. 298 , E237-E244, (2010)

ACTH and alpha-melanocyte-stimulating hormone (alpha-MSH) are both consecutively processed from proopiomelanocortin (POMC), which is synthesized in hypothalamic arcuate neurons innervating the paraventricular nuclei (PVN). POMC secretion/synthesis is regulate...

ACTH (Acthar Gel) Reduces Toxic SOD1 Protein Linked to Amyotrophic Lateral Sclerosis in Transgenic Mice: A Novel Observation.

PLoS ONE 10 , e0125638, (2015)

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with a complex etiology and pathology that makes the development of new therapies difficult. ACTH has neurotrophic and myotrophic effects, but has not been tested in an ALS mouse model. The G9...