eicosapentaenoic acid ethyl ester
eicosapentaenoic acid ethyl ester structure
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Common Name | eicosapentaenoic acid ethyl ester | ||
|---|---|---|---|---|
| CAS Number | 73310-10-8 | Molecular Weight | 330.504 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 417.0±34.0 °C at 760 mmHg | |
| Molecular Formula | C22H34O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 103.1±24.0 °C | |
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Protective effects of prescription n-3 fatty acids against impairment of spatial cognitive learning ability in amyloid β-infused rats.
Food Funct. 2(7) , 386-94, (2011) Deposition of amyloid β peptide (Aβ) into the brain causes cognitive impairment. We investigated whether prescription pre-administration of n-3 fatty acids improves cognitive learning ability in young rats and whether it protects against learning ability impa... |
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Usefulness of colon targeted DHA and EPA as novel diabetes medications that promote intrinsic GLP-1 secretion.
J. Control. Release 132(2) , 99-104, (2008) Glucagon-like peptide-1 (GLP-1) is a gut-derived peptide secreted from intestinal L-cells and now considered as an ideal diabetic medicine. Recently, it was reported that the unsaturated fatty acid alpha-linoleic acid promotes the secretion of GLP-1 via a G p... |
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Identification of inflammatory and proresolving lipid mediators in bone marrow and their lipidomic profiles with ovariectomy and omega-3 intake.
Am. J. Hematol. 83(6) , 437-45, (2008) Newly described lipoxygenase (LOX)-generated lipid mediators, that is, resolvins and protectins as well as lipoxins, are both anti-inflammatory and proresolving. We aimed to determine whether these lipid mediators are present in bone marrow and whether their ... |
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Highly purified eicosapentaenoic acid prevents the progression of hepatic steatosis by repressing monounsaturated fatty acid synthesis in high-fat/high-sucrose diet-fed mice.
Prostaglandins Leukot. Essent. Fatty Acids 80(4) , 229-38, (2009) Eicosapentaenoic acid (EPA) is a member of the family of n-3 polyunsaturated fatty acids (PUFAs) that are clinically used to treat hypertriglyceridemia. The triglyceride (TG) lowering effect is likely due to an alteration in lipid metabolism in the liver, but... |
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Does eicosapentaenoic acid (EPA) inhibit cerebral vasospasm in patients after aneurysmal subarachnoid hemorrhage?
Acta Neurol. Scand 118(1) , 54-9, (2008) Cerebral vasospasm following subarachnoid hemorrhage (SAH) is a significant cause of morbidity and mortality and recent studies indicate that Rho-kinase plays an important role in the occurrence of such cerebral vasospasm. Eicosapentaenoic acid (EPA), an n-3 ... |
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Oral administration of eicosapentaenoic acid or docosahexaenoic acid modifies cardiac function and ameliorates congestive heart failure in male rats.
J. Nutr. 144(4) , 467-74, (2014) This study assessed the effects of eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA) on normal cardiac function (part 1) and congestive heart failure (CHF) (part 2) through electrocardiogram analysis and determination of EPA, DHA, and arachidonic acid... |
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Antitumor and antimetastatic actions of eicosapentaenoic acid ethylester and its by-products formed during accelerated stability testing.
Cancer Sci. 96(7) , 441-50, (2005) The aim of the present work was to compare the effects of eicosapentaenoic acid (EPA) ethylester and EPA derivatives (EPAD) on tumor growth and metastasis to the lung in tumor-bearing mice. Because EPA is very unstable during long-term storage, the EPAD were ... |
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A pilot open case series of ethyl-EPA supplementation in the treatment of anorexia nervosa.
Prostaglandins Leukot. Essent. Fatty Acids 71(4) , 205-9, (2004) Anorexia nervosa (AN) carries the highest risk of morbidity and mortality amongst psychiatric disorders. The efficacy of current treatment approaches is limited. Despite the fat-phobic nature of the disease, poly-unsaturated fatty acids (PUFAs) have not recei... |
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Effects of eicosapentaenoic acids on oxidative stress and plasma fatty acid composition in patients with lupus nephritis.
In Vivo 19(5) , 879-82, (2005) Eicosapentaenoic acid (EPA) is one of the major components of fish oil, which was reported to have antiatherogenic, anti-inflammatory and immune suppressive effects. In the present study, highly purified EPA was administered to patients with lupus nephritis a... |
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Improving effect of ethyl eicosapentanoate on statin-induced rhabdomyolysis in Eisai hyperbilirubinemic rats.
Biochem. Biophys. Res. Commun. 340(1) , 215-20, (2006) The effect of ethyl eicosapentanoate (EPA-E) on statin-induced rhabdomyolysis was investigated by co-administration of EPA-E and pravastatin (PV), as a typical statin, to Eisai hyperbilirubinemic rats (EHBR). It was confirmed that the plasma PV concentration ... |