Apramycin sulfate
Apramycin sulfate structure
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Common Name | Apramycin sulfate | ||
|---|---|---|---|---|
| CAS Number | 65710-07-8 | Molecular Weight | 637.656 | |
| Density | 1.56 | Boiling Point | 949.8ºC at 760 mmHg | |
| Molecular Formula | C21H43N5O15S | Melting Point | >168ºC (dec.) | |
| MSDS | Chinese USA | Flash Point | 528.2ºC | |
| Symbol |
GHS08 |
Signal Word | Danger | |
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Genomic analysis reveals distinct concentration-dependent evolutionary trajectories for antibiotic resistance in Escherichia coli.
DNA Res. 21(6) , 711-26, (2014) Evolution of bacteria under sublethal concentrations of antibiotics represents a trade-off between growth and resistance to the antibiotic. To understand this trade-off, we performed in vitro evolution of laboratory Escherichia coli under sublethal concentrat... |
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Field trial evaluating changes in prevalence and patterns of antimicrobial resistance among Escherichia coli and Enterococcus spp. isolated from growing broilers medicated with enrofloxacin, apramycin and amoxicillin
Vet. Microbiol. 139(3-4) , 284-92, (2009) The present study investigates, under field conditions, the influence of antimicrobial administration on prevalence and patterns of antimicrobial resistance among Escherichia coli and Enterococcus spp. isolated from growing broilers. For this purpose, a group... |
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Enhancement of bacterial competitive fitness by apramycin resistance plasmids from non-pathogenic Escherichia coli.
Biol. Lett. 2(3) , 463-5, (2006) The study of antibiotic resistance has in the past focused on organisms that are pathogenic to humans or animals. However, the development of resistance in commensal organisms is of concern because of possible transfer of resistance genes to zoonotic pathogen... |
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Apramycin and gentamicin resistances in indicator and clinical Escherichia coli isolates from farm animals in Korea.
Foodborne Pathog. Dis. 8(1) , 119-23, (2011) A total of 1921 Escherichia coli isolated from healthy animals (501 from cattle, 832 from pigs, and 588 from chickens) and 237 isolates from diseased pigs were tested to determine the prevalence of apramycin and gentamicin resistance in Korea during 2004-2007... |
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Resistance patterns and detection of aac(3)-IV gene in apramycin-resistant Escherichia coli isolated from farm animals and farm workers in northeastern of China.
Res. Vet. Sci. 87(3) , 449-54, (2009) The aminoglycoside apramycin has been used widely in animal production in China since 1999. This study was aimed to investigate the resistance pattern of apramycin-resistant Escherichia coli isolated from farm animals and farm workers in northeastern of China... |
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Glycine origin of the methyl substituent on C7'-N of octodiose for the biosynthesis of apramycin.
Sci. China,. C, Life Sci. 49(4) , 362-9, (2006) Apramycin is unique in the aminoglycoside family due to its octodiose moiety. However, either the biosynthesis process or the precursors involved are largely unknown. Addition of glycine, as well as serine or threonine, to the Streptomyces tenebrabrius UD2 fe... |
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Structural features and oxidative stress towards plasmid DNA of apramycin copper complex.
Dalton Trans. (7) , 1123-30, (2009) The interaction of apramycin with copper at different pH values was investigated by potentiometric titrations and EPR, UV-vis and CD spectroscopic techniques. The Cu(II)-apramycin complex prevailing at pH 6.5 was further characterized by NMR spectroscopy. Met... |
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Evaluation of a survey approach to estimating the prevalence of cattle carrying antimicrobial-resistant Escherichia coli.
Vet. J. 175(3) , 416-8, (2008) A random survey of farms in the Highlands and Islands of Scotland provides estimated of the prevalence of calves, finishers and cows carrying ampicillin, apramycin and/or nalidixic acid resistant Escherichia coli. While the survey provides information on the ... |
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Marker removal from actinomycetes genome using Flp recombinase.
Gene 419(1-2) , 43-7, (2008) We report here a system for the functional expression of the Flp recombinase in several actinomycetes: Streptomyces coelicolor, S. lividans, and Saccharotrix espanaensis. We have constructed a synthetic gene encoding the Flp recombinase with a GC content of 6... |
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Synthesis, separation, and characterization of amphiphilic sulfated oligosaccharides enabled by reversed-phase ion pairing LC and LC-MS methods.
Carbohydr. Res. 346(17) , 2792-800, (2011) Synthesis of amphiphilic oligosaccharides is problematic because traditional methods for separating and purifying oligosaccharides, including sulfated oligosaccharides, are generally not applicable to working with amphiphilic sugars. We report here RPIP-LC an... |