Flunixin Meglumine
Flunixin Meglumine structure
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Common Name | Flunixin Meglumine | ||
|---|---|---|---|---|
| CAS Number | 42461-84-7 | Molecular Weight | 491.458 | |
| Density | 1.403 g/cm3 | Boiling Point | 378.7ºC at 760 mmHg | |
| Molecular Formula | C21H28F3N3O7 | Melting Point | 136-138ºC | |
| MSDS | Chinese USA | Flash Point | 182.8ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Pharmacokinetics and effects on thromboxane B2 production following intravenous administration of flunixin meglumine to exercised thoroughbred horses.
J. Vet. Pharmacol. Ther. 38 , 313-20, (2015) Flunixin meglumine is commonly used in horses for the treatment of musculoskeletal injuries. The current ARCI threshold recommendation is 20 ng/mL when administered at least 24 h prior to race time. In light of samples exceeding the regulatory threshold at 24... |
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Gene expression analyses identify Narp contribution in the development of L-DOPA-induced dyskinesia.
J. Neurosci. 35(1) , 96-111, (2015) In Parkinson's disease, long-term dopamine replacement therapy is complicated by the appearance of L-DOPA-induced dyskinesia (LID). One major hypothesis is that LID results from an aberrant transcriptional program in striatal neurons induced by L-DOPA and tri... |
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Registered report: the microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44.
Elife 4 , e06434, (2015) The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of selected experiments from a number of high-profile papers in the field of cancer biology. The papers, whic... |
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Effects of L-glutamine supplementation on maternal and fetal hemodynamics in gestating ewes exposed to alcohol.
Amino Acids 46(8) , 1981-96, (2014) Not much is known about effects of gestational alcohol exposure on maternal and fetal cardiovascular adaptations. This study determined whether maternal binge alcohol exposure and L-glutamine supplementation could affect maternal-fetal hemodynamics and fetal ... |
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Enhancement of endocannabinoid signaling protects against cocaine-induced neurotoxicity.
Toxicol. Appl. Pharmacol. 286 , 178-87, (2015) Cocaine is an addictive substance with a potential to cause deleterious effects in the brain. The strategies for treating its neurotoxicity, however, are limited. Evidence suggests that the endocannabinoid system exerts neuroprotective functions against vario... |
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Liquid storage of equine semen: Assessing the effect of d-penicillamine on longevity of ejaculated and epididymal stallion sperm.
Anim. Reprod. Sci. 159 , 155-62, (2015) Short-term storage of equine sperm at 5°C in an extender containing milk and/or egg yolk components is common practice in the equine breeding industry. Sperm motility, viability, DNA integrity and, consequently, fertilizing ability decline over time, partly d... |
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Experimental uses of flunixin meglumine and phenylbutazone in food-producing animals.
J. Am. Vet. Med. Assoc. 194(1) , 45-9, (1989) Presently, in the United States, there are no nonsteroidal anti-inflammatory drugs, except aspirin, that are approved for use in animals intended for food production. Use of phenylbutazone, flunixin meglumine, and dipyrone for treatment of food animals may be... |
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Modified lamellar keratoplasties for the treatment of deep stromal abscesses in horses.
Vet. Ophthalmol. 18 , 393-403, (2015) To describe a surgical modification of deep lamellar endothelial keratoplasty (DLEK) and posterior lamellar keratoplasty (PLK) procedures, to facilitate surgery on standing horses under-sedation.Four client-owned horses, for which the owners declined surgery ... |
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Cardiovascular complications following chronic treatment with cocaine and testosterone in adolescent rats.
PLoS ONE 9(8) , e105172, (2014) Concomitant use of anabolic androgenic steroids and cocaine has increased in the last years. However, the effects of chronic exposure to these substances during adolescence on cardiovascular function are unknown. Here, we investigated the effects of treatment... |
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Equine orbital fractures: a review of 18 cases (2006-2013).
Vet. Ophthalmol. 17 Suppl 1 , 97-106, (2014) To review the clinical features, treatments, complications, and outcomes of horses with traumatic orbital fractures.Retrospective study.Eighteen horses with confirmed orbital fractures.Medical records of horses presenting with orbital fractures between 2006 a... |