Amikacin sulfate
Amikacin sulfate structure
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Common Name | Amikacin sulfate | ||
|---|---|---|---|---|
| CAS Number | 39831-55-5 | Molecular Weight | 781.760 | |
| Density | N/A | Boiling Point | 981.8ºC at 760 mmHg | |
| Molecular Formula | C22H47N5O21S2 | Melting Point | 220-230ºC | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Nitrotriazole- and imidazole-based amides and sulfonamides as antitubercular agents.
Antimicrob. Agents Chemother. 58(11) , 6828-36, (2014) Twenty-three 3-nitrotriazole-based and 2-nitroimidazole-based amides and sulfonamides were screened for antitubercular (anti-TB) activity in aerobic Mycobacterium tuberculosis H37Rv by using the BacTiter-Glo (BTG) microbial cell viability assay. In general, 3... |
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Simple and accurate quantitative analysis of 20 anti-tuberculosis drugs in human plasma using liquid chromatography-electrospray ionization-tandem mass spectrometry.
J. Pharm. Biomed. Anal. 102 , 9-16, (2014) A simple and accurate liquid chromatography (LC)-tandem mass spectrometry (MS/MS) method for the quantitation of 20 anti-tuberculosis (anti-TB) drugs in human plasma, was developed as a tool for therapeutic drug monitoring. Two protein precipitation methods w... |
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Interactions of amikacin with the RNA model of the ribosomal A-site: computational, spectroscopic and calorimetric studies.
Biochimie 102 , 188-202, (2014) Amikacin is a 2-deoxystreptamine aminoglycoside antibiotic possessing a unique l-HABA (l-(-)-γ-amino-α-hydroxybutyric acid) group and applied in the treatment of hospital-acquired infections. Amikacin influences bacterial translation by binding to the decodin... |
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Incidence and risk factors for extensively drug-resistant tuberculosis in Delhi region.
PLoS ONE 8(2) , e55299, (2013) India with a major burden of multidrug-resistant tuberculosis (MDR-TB) does not have national level data on this hazardous disease. Since 2006, emergence of extensively drug-resistant TB (XDR-TB) is considered a serious threat to global TB control. This study... |
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The role of topical antibiotic prophylaxis to prevent endophthalmitis after intravitreal injection.
Ophthalmology 121(1) , 283-9, (2014) To compare the incidence of endophthalmitis after intravitreal injection with and without topical postinjection antibiotic prophylaxis.Retrospective case-control study.All patients treated with intravitreal injection of ranibizumab, bevacizumab, or aflibercep... |
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Endophthalmitis caused by streptococcal species: clinical settings, microbiology, management, and outcomes.
Am. J. Ophthalmol. 157(4) , 774-780.e1, (2014) To report the clinical settings, antibiotic susceptibilities, and outcomes of endophthalmitis caused by Streptococcus species.Retrospective, observational case series.Single-center study evaluating all patients with culture-positive endophthalmitis caused by ... |
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Delivery of aerosolized liposomal amikacin as a novel approach for the treatment of nontuberculous mycobacteria in an experimental model of pulmonary infection.
PLoS ONE 9(9) , e108703, (2014) Pulmonary infections caused by nontuberculous mycobacteria (NTM) are an increasing problem in individuals with chronic lung conditions and current therapies are lacking. We investigated the activity of liposomal amikacin for inhalation (LAI) against NTM in vi... |
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A model portraying experimental loss of hair cell: the use of distortion product otoacoustic emission in the assessment of rat's ear.
Pak. J. Pharm. Sci. 26(4) , 767-71, (2013) The use of rats in research academies to study deafness is widespread, meanwhile medicinal methods to eliminate hair cells is also increasing. Thus, aminoglycosides and loop diuretics have grasped more attention. This study aimed at establishing an animal mod... |
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Amikacin, kanamycin and tobramycin binding to melanin in the presence of Ca(2+) and Mg(2+) ions.
Acta Pol. Pharm. 69(6) , 1035-41, (2012) The aim of the presented work was to examine the interaction of amikacin, kanamycin and tobramycin with melanin in the presence of Ca(2+ )and Mg(2+) ions. It has been demonstrated that the analyzed aminoglycosides form complexes with melanin in the presence o... |
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In vitro synergistic effect of ciprofloxacin with aminoglycosides against multidrug resistant-Pseudomonas aeruginosa.
Pak. J. Pharm. Sci. 26(5) , 1041-4, (2013) Pseudomonas aeruginosa is an increasingly prevalent nosocomial human pathogen. Infections with multidrug-resistant (MDR) P. aeruginosa are currently a treatment challenge and requires search for better treatment options.To determine in vitro synergistic effec... |