(2S)-Methoxy(phenyl)acetic acid
(2S)-Methoxy(phenyl)acetic acid structure
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Common Name | (2S)-Methoxy(phenyl)acetic acid | ||
|---|---|---|---|---|
| CAS Number | 3966-32-3 | Molecular Weight | 166.174 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 283.8±0.0 °C at 760 mmHg | |
| Molecular Formula | C9H10O3 | Melting Point | 64-67ºC | |
| MSDS | Chinese USA | Flash Point | 116.1±15.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Discovery of inhibitors of the mitotic kinase TTK based on N-(3-(3-sulfamoylphenyl)-1H-indazol-5-yl)-acetamides and carboxamides.
Bioorg. Med. Chem. 22(17) , 4968-97, (2014) TTK kinase was identified by in-house siRNA screen and pursued as a tractable, novel target for cancer treatment. A screening campaign and systematic optimization, supported by computer modeling led to an indazole core with key sulfamoylphenyl and acetamido m... |
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B.M. Trost et al.
J. Org. Chem. 51 , 2370, (1986)
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J. Org. Chem. 59 , 4202, (1994)
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HPLC-based method for determination of absolute configuration of alpha-chiral amines.
Anal. Chem. 65 , 1456, (1993) We introduce a novel, HPLC-based method for facile determination of the absolute configuration of alpha-chiral amines. Our method is easily applied to a variety of compounds, including amino acid derivatives. The method involves initial derivatization of the ... |
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N-succinimidyl methoxyphenylacetic acid ester, an amine-directed chiral derivatizing reagent suitable for enzymatic scale resolutions.
Anal. Biochem. 178 , 177, (1989) A chiral derivatizing reagent, N-succinimidyl-2-(S)-methoxy-2-phenylacetic acid ester (SMPA), directed toward reaction with primary amine-containing compounds has been synthesized and characterized. This reagent is suitable for HPLC resolution from enzymatic-... |