Fenoterol hydrobromide
Fenoterol hydrobromide structure
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Common Name | Fenoterol hydrobromide | ||
|---|---|---|---|---|
| CAS Number | 1944-12-3 | Molecular Weight | 384.26500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H22BrNO4 | Melting Point | 226-228°C | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Inhaled Pharmacotherapy and Stroke Risk in Patients with Chronic Obstructive Pulmonary Disease: A Nationwide Population Based Study Using Two-Stage Approach.
PLoS ONE 10 , e0130102, (2015) Patients with chronic obstructive pulmonary disease (COPD) are at higher risk of stroke than those without COPD. This study aims to explore the impact of inhaled pharmacotherapy on stroke risk in COPD patients during a three-year follow-up, using a nationwide... |
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[Mechanism of the slow inotropic response of the mouse atrium mediated by the beta2-adrenoreceptor].
Ross. Fiziol. Zh. Im. I. M. Sechenova 97(11) , 1223-36, (2011) The abundant beta2-adrenoceptors (AR) expression was revealed in the mouse atrial cardiomyocytes, albeit its function is poorly understood. Recently we revealed the slow developing (for 20-40 min) positive inotropic effect in the mouse atrium which was induce... |
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Contribution of the extracellular cAMP-adenosine pathway to dual coupling of β2-adrenoceptors to Gs and Gi proteins in mouse skeletal muscle.
J. Pharmacol. Exp. Ther. 341(3) , 820-8, (2012) β(2)-Adrenoceptor (β(2)-AR) agonists increase skeletal muscle contractile force via activation of G(s) protein/adenylyl cyclases (AC) and increased generation of cAMP. Herein, we evaluated the possible dual coupling of β(2)-AR to G(s) and G(i) proteins and th... |
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Isolation and characterization of human primary enterocytes from small intestine using a novel method.
Scand. J. Gastroenterol. 47(11) , 1334-43, (2012) Cell culture studies of enterocytes are important in many fields. However, there are difficulties in obtaining cell lines from adult human intestine, such as microbial contamination of cultures from the tissue samples, short life span of enterocytes, overgrow... |
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Cannabinoid receptor activation correlates with the proapoptotic action of the β2-adrenergic agonist (R,R')-4-methoxy-1-naphthylfenoterol in HepG2 hepatocarcinoma cells.
J. Pharmacol. Exp. Ther. 343(1) , 157-66, (2012) Inhibition of cell proliferation by fenoterol and fenoterol derivatives in 1321N1 astrocytoma cells is consistent with β(2)-adrenergic receptor (β(2)-AR) stimulation. However, the events that result in fenoterol-mediated control of cell proliferation in other... |
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Thermodynamics and docking of agonists to the β(2)-adrenoceptor determined using [(3)H](R,R')-4-methoxyfenoterol as the marker ligand.
Mol. Pharmacol. 81(6) , 846-54, (2012) G protein-coupled receptors (GPCRs) are integral membrane proteins that change conformation after ligand binding so that they can transduce signals from an extracellular ligand to a variety of intracellular components. The detailed interaction of a molecule w... |
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Increased response to β₂-adrenoreceptor stimulation augments inhibition of IKr in heart failure ventricular myocytes.
PLoS ONE 7(9) , e46186, (2012) Increasing evidence indicates that the rapid component of delayed rectifier potassium current (I(Kr)) is modulated by α- and β-adrenergic stimulation. However, the role and mechanism regulating I(Kr) through β(2)-adrenoreceptor (β-AR) stimulation in heart fai... |
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Effect of fenoterol stereochemistry on the β2 adrenergic receptor system: ligand-directed chiral recognition.
Chirality 23 Suppl 1 , E1-6, (2011) The β(2) adrenergic receptor (β(2)-AR) is a model system for studying the ligand recognition process in G protein-coupled receptors. Fenoterol (FEN) is a β(2)-AR selective agonist that has two centers of chirality and exists as four stereoisomers. Radioligand... |
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Fenoterol functionally activates the β₃-adrenoceptor in human urinary bladder, comparison with rat and mouse: implications for drug discovery.
Eur. J. Pharmacol. 690(1-3) , 202-6, (2012) Fenoterol has been reported to be a potent and selective β(2)-adrenoceptor agonist and is currently used clinically to treat asthma. Electrical field stimulation (EFS) of isolated urinary bladder mimics the voiding contraction by stimulating parasympathetic n... |
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Anticholinergic therapy for acute asthma in children.
Cochrane Database Syst. Rev. 4 , CD003797, (2012) Inhaled anticholinergics as single agent bronchodilators (or in combination with beta(2)-agonists) are one of the several medications available for the treatment of acute asthma in children.To determine the effectiveness of only inhaled anticholinergic drugs ... |