N,N,N',N'-TETRAMETHYLBENZIDINE
N,N,N',N'-TETRAMETHYLBENZIDINE structure
|
Common Name | N,N,N',N'-TETRAMETHYLBENZIDINE | ||
|---|---|---|---|---|
| CAS Number | 366-29-0 | Molecular Weight | 240.34300 | |
| Density | 1.041g/cm3 | Boiling Point | 387.1ºC at 760 mmHg | |
| Molecular Formula | C16H20N2 | Melting Point | 193-195 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 173.4ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
Loss of Endocan tumorigenic properties after alternative splicing of exon 2.
BMC Cancer 8 , 14, (2008) Endocan was originally described as a dermatan sulfate proteoglycan found freely circulating in the blood. Endocan expression confers tumorigenic properties to epithelial cell lines or accelerate the growth of already tumorigenic cells. This molecule is the p... |
|
|
A triple-labeling method: HRP anterograde tract tracing combined with double immunofluorescent cell staining in developing neural tissue of the rat.
J. Neurosci. Methods 30 , 71, (1989) In this paper we describe a triple-labeling technique on a single section of developing nervous tissue. This labelling consists of a histochemical visualization of anterogradely transported horseradish peroxidase (HRP), within outgrowing rat corticospinal tra... |
|
|
Glutathione conjugate formation without N-demethylation during the peroxidase catalysed N-oxidation of N,N',N,N'-tetramethylbenzidine.
Chem. Biol. Interact. 61(1) , 61-74, (1987) The mechanism of peroxidative N-dealkylation of alkylamines proceeds via one-electron oxidation to the iminium cation which reacts with water to give the N-hydroxymethyl derivative which decomposes to formaldehyde and the N-demethylated product. This reaction... |
|
|
[Ferritin--a biocatalyst of aromatic amine oxidation].
Biokhimiia 61(2) , 308-21, (1996) The tetramethylbenzidine (TMB) oxidation kinetics dependent on spleen ferritin (FERR) has been studied in TMB-FERR-H2O2 (1) and TMB-FERR-O2 (2) systems at pH 4.2 and 6.0. At TMB concentrations below 6 mM, the dependencies of the initial rate for protein oxida... |
|
|
Application of colorimetric microdilution plate hybridization for rapid genetic identification of 22 Mycobacterium species.
J. Clin. Microbiol. 29(8) , 1596-603, (1991) Quantitative microdilution plate hybridization was used to identify 22 Mycobacterium species. DNAs of clinical strains were rapidly extracted and labeled with photoreactive biotin. Labeled DNAs were distributed into wells of a microdilution plate in which ref... |
|
|
Isolation of a highly active photosystem II preparation from Synechocystis 6803 using a histidine-tagged mutant of CP 47.
Biochim. Biophys. Acta 1409(1) , 50-7, (1998) Site-directed mutagenesis was used to produce a Synechocystis mutant containing a histidine tag at the C terminus of the CP 47 protein of Photosystem II. This mutant cell line, designated HT-3, exhibited slightly above normal rates of oxygen evolution and app... |
|
|
A double sandwich monoclonal enzyme immunoassay for detection of hepatitis B surface antigen.
J. Immunoassay 14 , 21, (1993) An enzyme immunoassay for detection of hepatitis B surface antigen based on the use of 3 monoclonal antibodies (mAbs) was developed: an IgM as capture and 2 IgG1 for detection. The system biotin-streptavidin was compared with direct conjugation of mAbs to per... |
|
|
Photoionization used as a tool for the study of biomembranes: fate of tetramethylbenzidine photocation in purple membrane.
Arch. Biochem. Biophys. 277(1) , 130-6, (1990) Photoionization of hydrophobic probes has been developed in micelles or synthetic vesicles. Studies of the yields, compartmentation, and lifetimes of the photo-produced charged species have gathered reliable information on the interfacial and structural prope... |
|
|
Brain stem projections of the aortic nerve in the cat: a study using tetramethyl benzidine as the substrate for horseradish peroxidase.
Brain Res. 188(1) , 23-32, (1980) The intra-axonal transport of horseradish peroxidase (HRP) has been used to trace the nodose ganglion and brain stem projections of a physiologically distinct nerve - the aortic depressor nerve - following electrophysiological identification. Tetramethyl benz... |
|
|
Additional factors influencing sensitivity in the tetramethyl benzidine method for horseradish peroxidase neurohistochemistry.
J. Histochem. Cytochem. 28(11) , 1255-9, (1980) In experiments that use horseradish peroxidase (HRP) and tetramethyl benzidine (TMB) for tracing neural connections, the activity of tissue-bound enzyme as well as the stability of the resultant reaction product are influenced by the duration of storage, the ... |