4-Chlorobenzylamine

4-Chlorobenzylamine Structure
4-Chlorobenzylamine structure
Common Name 4-Chlorobenzylamine
CAS Number 104-86-9 Molecular Weight 141.598
Density 1.2±0.1 g/cm3 Boiling Point 216.6±15.0 °C at 760 mmHg
Molecular Formula C7H8ClN Melting Point N/A
MSDS Chinese USA Flash Point 90.6±0.0 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

S-benzylisothiourea derivatives as small-molecule inhibitors of indoleamine-2,3-dioxygenase.

Bioorg. Med. Chem. Lett. 20 , 5126-9, (2010)

S-benzylisothiourea 3a was discovered by its ability to inhibit indoleamine-2,3-dioxygenase (IDO) in our screening program. Subsequent optimization of the initial hit 3a lead to the identification of sub-muM inhibitors 3r and 10h, both of which suppressed kyn...