3-Nitrophenylsulfonyl chloride
3-Nitrophenylsulfonyl chloride structure
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Common Name | 3-Nitrophenylsulfonyl chloride | ||
|---|---|---|---|---|
| CAS Number | 121-51-7 | Molecular Weight | 221.618 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 341.0±25.0 °C at 760 mmHg | |
| Molecular Formula | C6H4ClNO4S | Melting Point | 61-62 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 160.0±23.2 °C | |
| Symbol |
GHS05 |
Signal Word | Danger | |
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Synthesis and biological evaluation of imidazo[1,2-a]pyridine derivatives as novel PI3 kinase p110alpha inhibitors.
Bioorg. Med. Chem. 15(1) , 403-12, (2007) 3-{1-[(4-Fluorophenyl)sulfonyl]-1H-pyrazol-3-yl}-2-methylimidazo[1,2-a]pyridine, 2a, was discovered in our chemical library as a novel p110alpha inhibitor with an IC(50) of 0.67microM, through screening in a scintillation proximity assay. Optimization of the ... |
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Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4.
Bioorg. Med. Chem. Lett. 16 , 2842-2845, (2006) High-throughput screening of a small-molecule compound library resulted in the identification of a novel series of N-acyl 2-aminobenzimidazoles that are potent inhibitors of interleukin-1 receptor-associated kinase-4. |
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