2-(Trifluoromethoxy)benzaldehyde

2-(Trifluoromethoxy)benzaldehyde Structure
2-(Trifluoromethoxy)benzaldehyde structure
Common Name 2-(Trifluoromethoxy)benzaldehyde
CAS Number 94651-33-9 Molecular Weight 190.119
Density 1.3±0.1 g/cm3 Boiling Point 187.5±35.0 °C at 760 mmHg
Molecular Formula C8H5F3O2 Melting Point N/A
MSDS Chinese USA Flash Point 65.7±20.8 °C
Symbol GHS07
GHS07
Signal Word Warning

Trifluoromethoxy substituted anilines: metalation as the key step for structural elaboration.

J. Org. Chem. 68(12) , 4693-9, (2003)

Trifluoromethoxy-substituted anilines undergo hydrogen/lithium permutation ("metalation") with optional site selectivity depending on the N-protective group employed. N-tert-Butoxycarbonyl-2- and -4-(trifluoromethoxy)aniline react with tert-butyllithium at th...