4-Bromo-2-methylbenzoic acid

4-Bromo-2-methylbenzoic acid Structure
4-Bromo-2-methylbenzoic acid structure
Common Name 4-Bromo-2-methylbenzoic acid
CAS Number 68837-59-2 Molecular Weight 215.04
Density 1.6±0.1 g/cm3 Boiling Point 310.1±30.0 °C at 760 mmHg
Molecular Formula C8H7BrO2 Melting Point 180-184 °C
MSDS Chinese USA Flash Point 141.3±24.6 °C
Symbol GHS06
GHS06
Signal Word Danger

Preparation of novel anthranilic acids as antibacterial agents. Extensive evaluation of alternative amide bioisosteres connecting the A- and the B-rings.

Bioorg. Med. Chem. Lett. 17 , 2823, (2007)

In the past few years, a significant effort has been devoted by Pharmacia toward the discovery of novel antibiotics. We have recently described the identification of an anthranilic acid lead 1 and the optimization resulting in the advanced lead 2. In this rep...