Muscimol Hydrobromide
Muscimol Hydrobromide structure
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Common Name | Muscimol Hydrobromide | ||
|---|---|---|---|---|
| CAS Number | 18174-72-6 | Molecular Weight | 195.01500 | |
| Density | 1.291 g/cm3 | Boiling Point | 325ºC at 760 mmHg | |
| Molecular Formula | C4H7BrN2O2 | Melting Point | 172ºC | |
| MSDS | Chinese USA | Flash Point | 150.4ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Modulation of locomotor activation by the rostromedial tegmental nucleus.
Neuropsychopharmacology 40(3) , 676-87, (2015) The rostromedial tegmental nucleus (RMTg) is a strong inhibitor of dopamine neurons in the ventral tegmental area (VTA) reported to influence neurobiological and behavioral responses to reward omission, aversive and fear-eliciting stimuli, and certain drugs o... |
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Inactivation of the prelimbic or infralimbic cortex impairs decision-making in the rat gambling task.
Psychopharmacology 232 , 4481-91, (2015) Studies employing the Iowa Gambling Task (IGT) demonstrated that areas of the frontal cortex, including the ventromedial prefrontal cortex, orbitofrontal cortex (OFC), dorsolateral prefrontal cortex, and anterior cingulate cortex (ACC), are involved in the de... |
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Cholinergic, but not NMDA, receptors in the lateral entorhinal cortex mediate acquisition in trace eyeblink conditioning.
Hippocampus 25 , 1456-64, (2015) Anatomical and electrophysiological studies collectively suggest that the entorhinal cortex consists of several subregions, each of which is involved in the processing of different types of information. Consistent with this idea, we previously reported that t... |
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BDNF signaling in the VTA links the drug-dependent state to drug withdrawal aversions.
J. Neurosci. 34(23) , 7899-909, (2014) Drug administration to avoid unpleasant drug withdrawal symptoms has been hypothesized to be a crucial factor that leads to compulsive drug-taking behavior. However, the neural relationship between the aversive motivational state produced by drug withdrawal a... |
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Nucleus Accumbens and Posterior Amygdala Mediate Cue-Triggered Alcohol Seeking and Suppress Behavior During the Omission of Alcohol-Predictive Cues.
Neuropsychopharmacology 40 , 2555-65, (2015) Neurobiological mechanisms that influence behavior in the presence of alcohol-associated stimuli involve processes that organize behavior during the presence of these cues, and separately, regulation of behavior in their absence. However, little is known abou... |
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Vibrissa-based object localization in head-fixed mice.
J. Neurosci. 30 , 1947-67, (2010) Linking activity in specific cell types with perception, cognition, and action, requires quantitative behavioral experiments in genetic model systems such as the mouse. In head-fixed primates, the combination of precise stimulus control, monitoring of motor o... |
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Relief learning is distinguished from safety learning by the requirement of the nucleus accumbens.
Behav. Brain Res. 272 , 40-5, (2014) Aversive events induce aversive memories (fear learning) and can also establish appetitive memories. This is the case for cues associated with the cessation of an aversive event (relief learning) or occurring in an explicitly unpaired fashion (safety learning... |
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Methylmercury-Dependent Increases in Fluo4 Fluorescence in Neonatal Rat Cerebellar Slices Depend on Granule Cell Migrational Stage and GABAA Receptor Modulation.
J. Pharmacol. Exp. Ther. 356 , 2-12, (2015) Methylmercury (MeHg) disrupts cerebellar function, especially during development. Cerebellar granule cells (CGC), which are particularly susceptible to MeHg by unknown mechanisms, migrate during this process. Transient changes in intracellular Ca(2+) (Ca(2+) ... |
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Brief cortical deactivation early in life has long-lasting effects on multisensory behavior.
J. Neurosci. 34(21) , 7198-202, (2014) Detecting and locating environmental events are markedly enhanced by the midbrain's ability to integrate visual and auditory cues. Its capacity for multisensory integration develops in cats 1-4 months after birth but only after acquiring extensive visual-audi... |
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Spatial memory in nonhuman primates implanted with the subdural pharmacotherapy device.
Behav. Brain Res. 286 , 293-9, (2015) This study investigated the possible influence of the Subdural Pharmacotherapy Device (SPD) on spatial memory in 3 adult, male bonnet macaques (Macaca radiata). The device was implanted in and above the subdural/subarachnoid space and cranium overlaying the r... |