(2-Nitrophenyl)acetic acid

(2-Nitrophenyl)acetic acid Structure
(2-Nitrophenyl)acetic acid structure
Common Name (2-Nitrophenyl)acetic acid
CAS Number 3740-52-1 Molecular Weight 181.145
Density 1.4±0.1 g/cm3 Boiling Point 345.1±17.0 °C at 760 mmHg
Molecular Formula C8H7NO4 Melting Point 137-140 °C(lit.)
MSDS Chinese USA Flash Point 155.9±9.4 °C
Symbol GHS07
GHS07
Signal Word Warning

Studies on the catalytic behaviour of a cholinesterase-like abzyme in an AOT microemulsion system.

J. Biotechnol. 97(2) , 177-82, (2002)

The hydrolytic activity of a monoclonal catalytic antibody (9A8) (abzyme) with acetylcholinesterase-like activity was investigated in water-in-oil (w/o) microemulsions (reverse micelles) based on sodium bis-2-(ethylhexyl)sulfosuccinate (AOT) in isooctane, usi...

Molecular mechanism of uncaging CO2 from nitrophenylacetate provides general guidelines for improved ortho-nitrobenzyl cages.

ChemPhysChem 12(11) , 2077-80, (2011)

Femtosecond spectroscopy and quantum chemical calculations provide detailed insights into the specificities of the uncaging mechanism of CO2 from ortho-, meta-, and para-nitrophenylacetate. The emerging general principles allow a rational design of improved o...

Determination of the theophylline solubilizer salicylamide-O-acetic acid in serum and urine using high-performance liquid chromatography.

J. Pharm. Biomed. Anal. 3(5) , 469-75, (1985)

A high-performance liquid chromatographic method for the determination of the theophylline solubilizer salicylamide-O-acetic acid has been developed in the range 0.5 to 10 microg/ml for human serum and 5 to 400 microg/ml for urine. Reversed-phase ion-pair chr...

Mechanisms of cholinesterase inhibition by inorganic mercury.

FEBS J. 274(7) , 1849-61, (2007)

The poorly known mechanism of inhibition of cholinesterases by inorganic mercury (HgCl2) has been studied with a view to using these enzymes as biomarkers or as biological components of biosensors to survey polluted areas. The inhibition of a variety of choli...

Comparison of activation of CPT-11 by rabbit and human carboxylesterases for use in enzyme/prodrug therapy.

Clin. Cancer Res. 5(4) , 917-24, (1999)

Several recent studies have examined the possibility of producing tumor-specific cytotoxicity with various enzyme/ prodrug combinations. The enzymes are targeted to tumor cells either with antibodies (ADEPT, antibody directed enzyme prodrug therapy) or with v...

Leveraging a small-molecule modification to enable the photoactivation of rho GTPases.

ChemBioChem. 10(18) , 2855-7, (2009)