1,8-Naphthalenediol
1,8-Naphthalenediol structure
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Common Name | 1,8-Naphthalenediol | ||
|---|---|---|---|---|
| CAS Number | 569-42-6 | Molecular Weight | 160.169 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 375.4±15.0 °C at 760 mmHg | |
| Molecular Formula | C10H8O2 | Melting Point | 142-143ºC | |
| MSDS | Chinese USA | Flash Point | 193.5±15.0 °C | |
| Symbol |
GHS05 |
Signal Word | Danger | |
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Physicochemical characterization and antioxidant activity of melanin from a novel strain of Aspergillus bridgeri ICTF-201.
Lett. Appl. Microbiol. 53(3) , 350-8, (2011) The aim of the study is to isolate and characterize a melanin pigment from a new strain of Aspergillus bridgeri isolated from rhizosphere soil of Eucalyptus tree and to investigate its antioxidant activity.The extracellular pigment was alkali soluble, acid-re... |
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The influence of ortho- and para-diphenoloxidase substrates on pigment formation in black yeast-like fungi.
Stud. Mycol. 61 , 39-49, (2009) Dothideaceous black yeast-like fungi (BYF) are known to synthesise DHN-melanin that is inhibited by the systemic fungicide tricyclazole. The final step of the DHN melanin pathway is the conjoining of 1,8-DHN molecules to form the melanin polymer. There are se... |
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Pentaketide melanin biosynthesis in Aspergillus fumigatus requires chain-length shortening of a heptaketide precursor.
J. Biol. Chem. 276(31) , 29292-8, (2001) Chain lengths and cyclization patterns of microbial polyketides are generally determined by polyketide synthases alone. Fungal polyketide melanins are often derived from a pentaketide 1,8-dihydroxynaphthalene, and pentaketide synthases are used for synthesis ... |
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LAC2 encoding a secreted laccase is involved in appressorial melanization and conidial pigmentation in Colletotrichum orbiculare.
Mol. Plant Microbe Interact. 25(12) , 1552-61, (2012) Both Colletotrichum and Magnaporthe spp. develop appressoria pigmented with melanin, which is essential for fungal pathogenicity. 1,8-Dihydroxynaphthalene (1,8-DHN) is believed to be polymerized to yield melanin around the appresorial cell wall through the ox... |
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Pigment biosynthesis and virulence.
Contrib. Microbiol. 2 , 205-15, (1999)
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Antioxidant function of melanin in black fungi.
Infect. Immun. 63(12) , 4944-5, (1995) 1,8-Dihydroxynaphthalene melanin in Wangiella dermatitidis and Alternaria alternata was titrated in vivo with the oxidants permanganate, hypochlorite, and H2O2. Melanized strains neutralized more oxidant and withstood higher concentrations of permanganate and... |
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The developmentally regulated alb1 gene of Aspergillus fumigatus: its role in modulation of conidial morphology and virulence.
J. Bacteriol. 180(12) , 3031-8, (1998) Aspergillus fumigatus, an important opportunistic pathogen which commonly affects neutropenic patients, produces conidia with a bluish-green color. We identified a gene, alb1, which is required for conidial pigmentation. The alb1 gene encodes a putative polyk... |
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Scytalols A, B, C, and D and other modulators of melanin biosynthesis from Scytalidium sp. 36-93.
J. Antibiot. 51(4) , 387-93, (1998) From submerged cultures of Scytalidium sp. 36-93, ten metabolites were isolated due to their effects on dihydroxynaphthalene (DHN) or DOPA melanin biosynthesis. Four of the compounds, scytalols A (1a), B (1b), C (2) and D (3), are new secondary metabolites, t... |
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1,8-dihydroxynaphthalene (DHN)-melanin biosynthesis inhibitors increase erythritol production in Torula corallina, and DHN-melanin inhibits erythrose reductase.
Appl. Environ. Microbiol. 69(6) , 3427-34, (2003) The yeast Torula corallina is a strong erythritol producer that is used in the industrial production of erythritol. However, melanin accumulation during culture represents a serious problem for the purification of erythritol from the fermentation broth. Melan... |
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Pentaketide metabolites of melanin synthesis in the dematiaceous fungus Wangiella dermatitidis.
Arch. Microbiol. 137(4) , 324-8, (1984) Melanin synthesis in the dematiaceous, polymorphic hyphomycete Wangiella dermatitidis, a human pathogen, was investigated by biochemical and physiological techniques. Mutants with a decrease or loss in melanin synthesis were induced and isolated. Melanin prec... |