3,5-Bis(trifluoromethyl)benzylamine
3,5-Bis(trifluoromethyl)benzylamine structure
|
Common Name | 3,5-Bis(trifluoromethyl)benzylamine | ||
|---|---|---|---|---|
| CAS Number | 85068-29-7 | Molecular Weight | 243.149 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 165.5±35.0 °C at 760 mmHg | |
| Molecular Formula | C9H7F6N | Melting Point | 50-55 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 78.3±0.0 °C | |
| Symbol |
GHS05 |
Signal Word | Danger | |
|
Discovery of 3,5-bis(trifluoromethyl)benzyl L-arylglycinamide based potent CCR2 antagonists.
Bioorg. Med. Chem. Lett. 16(14) , 3735-9, (2006) Systematic modification of a screening lead yielded a class of potent glycinamide based CCR2 antagonists. The best compound (55, (2S)-N-[3,5-bis(trifluoromethyl)benzyl]-2-{[2-(1-piperidinyl)ethyl]amino}-2-(3-thienyl)acetamide) displayed good binding affinity ... |
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