succinylsulfathiazole
succinylsulfathiazole structure
|
Common Name | succinylsulfathiazole | ||
|---|---|---|---|---|
| CAS Number | 116-43-8 | Molecular Weight | 355.389 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C13H13N3O5S2 | Melting Point | 187 - 193ºC | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Arsenic urinary speciation in Mthfr deficient mice injected with sodium arsenate.
Toxicol. Lett. 215(3) , 214-8, (2012) In most mammalian species, arsenic biotransformation occurs primarily by biomethylation and reduction reactions, with dimethylarsinic acid being the predominant metabolite excreted in the urine. Methylenetetrahydrofolate reductase (Mthfr) plays a key role in ... |
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Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Eur. J. Med. Chem. 46 , 218-28, (2011) In order to minimize the high attrition rate that usually characterizes drug research and development projects, current medicinal chemists aim to characterize both pharmacological and ADME profiles at the beginning of drug R&D initiatives. Thus, the developme... |
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Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase.
J. Neurosci. 28 , 7219-7230, (2008) Folate deficiency and resultant increased homocysteine levels have been linked experimentally and epidemiologically with neurodegenerative conditions like stroke and dementia. Moreover, folate deficiency has been implicated in the pathogenesis of psychiatric ... |
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Gene-environment interactions reveal a homeostatic role for cholesterol metabolism during dietary folate perturbation in mice.
Physiol. Genomics 35 , 182-190, (2008) Dietary folate supplementation can dramatically reduce the severity and incidence of several common birth defects and adult diseases that are associated with anomalies in homocysteine and folate metabolism. The common polymorphisms that adversely affect these... |
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Homocysteine reduces protein S-nitrosylation in endothelium.
Int. J. Mol. Med. 34(5) , 1277-85, (2014) Hyperhomocysteinemia (HHcy) is a risk factor for cardiovascular disease. The S-nitrosylation of proteins is involved in the regulation of cardiovascular functions. However, whether homocysteine (Hcy) impairs vascular functions through the inhibition of protei... |
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Folate depletion impairs DNA excision repair in the colon of the rat.
Gut 43(1) , 93-9, (1998) Diminished folate status appears to promote colonic carcinogenesis by, as of yet, undefined mechanisms. Impaired DNA repair plays a significant role in the evolution of many colon cancers. Since folate is essential for the de novo synthesis of nucleotides and... |
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Estimation of sulfasuxidine and sulfathalidine.
Ariz. Med. 3 , 96-8, (1946)
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USE OF SULFASUXIDINE IN RESECTION OF CARCINOMA OF THE COLON-EFFECT ON INFECTION AND MORTALITY.
Calif. Med. 66(5) , 292-4, (1947)
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Influence of relative humidity on the adhesive properties of a model interactive system.
J. Pharm. Pharmacol. 40(7) , 453-8, (1988) The influence of relative humidity on the adhesive properties of model drug-carrier interactive systems was investigated using the centrifuge method. The degree of adhesion was quantified by determining the S50 from the adhesion profile. High ambient humidity... |
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Polyphosphazene membranes and microspheres in periodontal diseases and implant surgery.
Biomaterials 20(1) , 91-8, (1999) Membranes or microcapsules made from polyphosphazenes bearing amino acid side groups are proposed for the treatment of periodontal diseases. Polyphosphazene membranes, prepared with alanine ethyl ester and imidazole in the molar ratio of 80:20 as phosphorus s... |