N-Carbobenzoxy-β-alanine

N-Carbobenzoxy-β-alanine Structure
N-Carbobenzoxy-β-alanine structure
Common Name N-Carbobenzoxy-β-alanine
CAS Number 2304-94-1 Molecular Weight 223.225
Density 1.2±0.1 g/cm3 Boiling Point 435.9±38.0 °C at 760 mmHg
Molecular Formula C11H13NO4 Melting Point 100-105°C
MSDS Chinese USA Flash Point 217.4±26.8 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

Functionalized nanocarrier combined seizure-specific vector with P-glycoprotein modulation property for antiepileptic drug delivery.

Biomaterials 74 , 64-76, (2015)

Despite optimal therapeutic regimen with currently available antiepileptic drugs (AEDs), approximately a third of epilepsy patients remain drug refractory. Region-specific overexpression of multidrug efflux transporters at the blood-brain barrier, such as P-g...

Asymmetric synthesis of trans-2,3-piperidinedicarboxylic acid and trans-3,4-piperidinedicarboxylic acid derivatives.

J. Org. Chem. 67 , 865-870, (2002)

Asymmetric syntheses of (2S,3S)-3-(tert-butoxycarbonyl)-2-piperidinecarboxylic acid (1b), (3R,4S)-4-(tert-butoxycarbonyl)-3-piperidinecarboxylic acid (2b), and their corresponding N-Boc and N-Cbz protected analogues 8a,b and 17a,b are described. Enantiomerica...

Synthesis and anticonvulsant activity of N-benzyloxycarbonyl-amino acid prodrugs of phenytoin.

J. Pharm. Pharmacol. 51 , 549-553, (1999)

Glycine, which has weak anticonvulsant properties, has been shown to potentiate the activity of several antiepileptic drugs but not phenytoin. Recently, studies have shown that N-(benzyloxycarbonyl)glycine (Z-glycine) antagonized seizures more than glycine in...