H-Arg(NO2)-OH
H-Arg(NO2)-OH structure
|
Common Name | H-Arg(NO2)-OH | ||
|---|---|---|---|---|
| CAS Number | 2149-70-4 | Molecular Weight | 219.199 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 462.4±55.0 °C at 760 mmHg | |
| Molecular Formula | C6H13N5O4 | Melting Point | 257 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 233.5±31.5 °C | |
|
Role of Telokin in Regulating Murine Gastric Fundus Smooth Muscle Tension.
PLoS ONE 10 , e0134876, (2015) Telokin phosphorylation by cyclic GMP-dependent protein kinase facilitates smooth muscle relaxation. In this study we examined the relaxation of gastric fundus smooth muscles from basal tone, or pre-contracted with KCl or carbachol (CCh), and the phosphorylat... |
|
|
Network analysis of immunotherapy-induced regressing tumours identifies novel synergistic drug combinations.
Sci. Rep. 5 , 12298, (2015) Cancer immunotherapy has shown impressive results, but most patients do not respond. We hypothesized that the effector response in the tumour could be visualized as a complex network of interacting gene products and that by mapping this network we could predi... |
|
|
Evidence for the gastric cytoprotective effect of centrally injected agmatine.
Brain Res. Bull. 108 , 51-9, (2014) Agmatine (decarboxylated arginine) exerts cytoprotective action in several tissues, such as in the brain, heart or kidneys, but there is still controversy over the effects of agmatine on the gastric mucosa. The aim of the present study was to reveal the poten... |
|
|
Relaxant effect of flavonoid naringenin on contractile activity of rat colonic smooth muscle.
J. Ethnopharmacol. 155(2) , 1177-83, (2014) Disturbed gastrointestinal (GI) motility can be associated with smooth muscle abnormalities and dysfunction. Exploring innovative approaches that can modulate the disturbed colonic motility are of great importance for clinical therapeutics. Naringenin, a flav... |
|
|
Knockdown of angiopoietin like-2 protects against angiotensin II-induced cerebral endothelial dysfunction in mice.
Am. J. Physiol. Heart Circ. Physiol. 308(5) , H386-97, (2015) Angiopoietin like-2 (angptl2) is a circulating pro-inflammatory and pro-oxidative protein, but its role in regulating cerebral endothelial function remains unknown. We hypothesized that in mice knockdown (KD) of angptl2, cerebral endothelial function would be... |
|
|
Prion protein and copper cooperatively protect neurons by modulating NMDA receptor through S-nitrosylation.
Antioxid. Redox Signal. 22(9) , 772-84, (2015) Several neurodegenerative disorders show alterations in glutamatergic synapses and increased susceptibility to excitotoxicity. Mounting evidence suggests a central role for the cellular prion protein (PrP(C)) in neuroprotection. Therefore, the loss of PrP(C) ... |
|
|
Changes in nitrergic and tachykininergic pathways in rat proximal colon in response to chronic treatment with otilonium bromide.
Neurogastroenterol. Motil. 27(7) , 997-1009, (2015) Otilonium bromide (OB) is used as a spasmolytic drug in the treatment of the functional bowel disorder irritable bowel syndrome. Although its acute effects on colonic relaxation are well-characterized, little is known about the effects of chronic administrati... |
|
|
Bimodal effect of oxidative stress in internal anal sphincter smooth muscle.
Am. J. Physiol. Gastrointest. Liver Physiol. 309 , G292-300, (2015) Changes in oxidative stress may affect basal tone and relaxation of the internal anal sphincter (IAS) smooth muscle in aging. We examined this issue by investigating the effects of the oxidative stress inducer 6-anilino-5,8-quinolinedione (LY-83583) in basal ... |
|
|
Pannexin 1 facilitates arterial relaxation via an endothelium-derived hyperpolarization mechanism
FEBS Lett. 589(10) , 1164-70, (2015) • We studied endothelium-dependent relaxations in control (WT) and Panx1−/− (KO) mice. • The EDH-like component of endothelium-dependent relaxation is impaired in KO mice. • Blockade of purinergic signaling reduces EDH-like component in WT, but not in KO mice... |
|
|
Reduced vascular responses to soluble guanylyl cyclase but increased sensitivity to sildenafil in female rats with type 2 diabetes.
Am. J. Physiol. Heart Circ. Physiol. 309 , H297-304, (2015) Impaired nitric oxide (NO), soluble guanylyl cyclase (sGC), and cyclic guanosine monophosphate (cGMP) signaling (NO-sGC-cGMP) has been implicated in the pathogenesis of diabetic vascular dysfunction. Efforts to directly target this signaling have led to the d... |