TTNPB
TTNPB structure
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Common Name | TTNPB | ||
|---|---|---|---|---|
| CAS Number | 71441-28-6 | Molecular Weight | 348.478 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 486.8±44.0 °C at 760 mmHg | |
| Molecular Formula | C24H28O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 228.6±23.1 °C | |
| Symbol |
GHS07, GHS08 |
Signal Word | Danger | |
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Retinoids Bias Integrin Expression and Function in Cutaneous T-Cell Lymphoma.
J. Invest. Dermatol. 135 , 2102-8, (2015) Cutaneous T-cell lymphoma (CTCL) is a heterogeneous group of malignancies characterized by accumulation of malignant T-cells within the skin. Retinoids, metabolic derivatives, and synthetic analogs of vitamin A embody an effective CTCL therapy with over three... |
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Additive Effects of Retinoic Acid (RA) and Bone Morphogenetic Protein 4 (BMP-4) Apoptosis Signaling in Retinoblastoma Cell Lines.
PLoS ONE 10 , e0131467, (2015) Retinoids have been shown to serve promising therapeutic agents for human cancers, e.g. the treatment of neuroblastoma. Synthetic retinoids, specific for particular retinoic acid (RA) receptors, are tested as new therapy strategies. In the present study, appl... |
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The bioactive lipid 4-hydroxyphenyl retinamide inhibits flavivirus replication.
Antimicrob. Agents Chemother. 59(1) , 85-95, (2014) Dengue virus (DENV), a member of the Flaviviridae family, is a mosquito-borne pathogen and the cause of dengue fever. The increasing prevalence of DENV worldwide heightens the need for an effective vaccine and specific antivirals. Due to the dependence of DEN... |
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Zic1 controls placode progenitor formation non-cell autonomously by regulating retinoic acid production and transport.
Nat. Commun. 6 , 7476, (2015) All cranial placode progenitors arise from a common precursor field anterior to the neural plate, the pre-placodal region (PPR). We showed that transcription factor Zic1, expressed at the anterior neural plate, is necessary and sufficient to promote placode f... |
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Retinoid X receptors orchestrate osteoclast differentiation and postnatal bone remodeling.
J. Clin. Invest. 125(2) , 809-23, (2015) Osteoclasts are bone-resorbing cells that are important for maintenance of bone remodeling and mineral homeostasis. Regulation of osteoclast differentiation and activity is important for the pathogenesis and treatment of diseases associated with bone loss. He... |
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TALEN/CRISPR-mediated eGFP knock-in add-on at the OCT4 locus does not impact differentiation of human embryonic stem cells towards endoderm.
PLoS ONE 9(12) , e114275, (2014) Human embryonic stem cells (hESCs) have great promise as a source of unlimited transplantable cells for regenerative medicine. However, current progress on producing the desired cell type for disease treatment has been limited due to an insufficient understan... |
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A mollusk retinoic acid receptor (RAR) ortholog sheds light on the evolution of ligand binding.
Endocrinology 155(11) , 4275-86, (2014) Nuclear receptors are transcription factors that regulate networks of target genes in response to small molecules. There is a strong bias in our knowledge of these receptors because they were mainly characterized in classical model organisms, mostly vertebrat... |
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Farnesoid X receptor-dependent and -independent pathways mediate the transcriptional control of human fibroblast growth factor 19 by vitamin A.
Biochim. Biophys. Acta 1859 , 381-92, (2016) Fibroblast growth factor 19 (FGF19) is a gut-derived hormone that controls bile acid (BA), carbohydrate and lipid metabolism. Whereas strong evidence supports a key role of BAs and farnesoid X receptor (FXR) for the control of FGF19 expression, information on... |
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Cell Therapy Using Human Induced Pluripotent Stem Cell-Derived Renal Progenitors Ameliorates Acute Kidney Injury in Mice.
Stem Cells Transl. Med. 4 , 980-92, (2015) Acute kidney injury (AKI) is defined as a rapid loss of renal function resulting from various etiologies, with a mortality rate exceeding 60% among intensive care patients. Because conventional treatments have failed to alleviate this condition, the developme... |
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Retinoic acid regulates myelin formation in the peripheral nervous system.
Glia 58(12) , 1451-64, (2010) Understanding the mechanisms that control myelin formation is essential for the development of demyelinating diseases treatments. All-trans-retinoic acid (RA) plays an essential role during the development of the nervous system as a potent regulator of morpho... |