2-Hydroxyoctanoic acid

2-Hydroxyoctanoic acid Structure
2-Hydroxyoctanoic acid structure
Common Name 2-Hydroxyoctanoic acid
CAS Number 617-73-2 Molecular Weight 160.21
Density 1.0±0.1 g/cm3 Boiling Point 289.0±13.0 °C at 760 mmHg
Molecular Formula C8H16O3 Melting Point 66-68 °C
MSDS Chinese USA Flash Point 142.8±16.3 °C
Symbol GHS07
GHS07
Signal Word Warning

Inhibition of a medium chain acyl-CoA synthetase involved in glycine conjugation by carboxylic acids.

Biochem. Pharmacol. 52 , 1643-1646, (1996)

Molecular characteristics of carboxylic acids were investigated for the ability to inhibit a purified medium chain acyl-CoA synthetase, using hexanoic acid as a substrate. Salicylic acid, 4-methylsalicylic acid, 2-hydroxynaphtoic acid, and 2-hydroxyoctanoic a...

Determination of the enantiomers of alpha-hydroxy- and alpha-amino acids in capillary electrophoresis with contactless conductivity detection.

Electrophoresis 31 , 2044-2048, (2010)

The enantiomers of the anions of five alpha-hydroxy acids, namely lactic acid, alpha-hydroxybutyric acid, 2-hydroxycaproic acid, 2-hydroxyoctanoic acid and 2-hydroxydecanoic acid, as well as the two alpha-amino acids aspartic acid and glutamic acid, were base...

3-Hydroxydicarboxylic aciduria due to long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency associated with sudden neonatal death: protective effect of medium-chain triglyceride treatment.

Eur. J. Pediatr. 150(3) , 190-5, (1991)

Two siblings were found to be affected by long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency, one of which died suddenly and unexpectedly on the 3rd day of life suffering from extreme hypoketotic hypoglycaemia. The younger sibling started to have feeding p...

Identification and characterization of HAOX1, HAOX2, and HAOX3, three human peroxisomal 2-hydroxy acid oxidases.

J. Biol. Chem. 275(17) , 12590-7, (2000)

Computer-based approaches identified three distinct human 2-hydroxy acid oxidase genes, HAOX1, HAOX2, and HAOX3, that encode proteins with significant sequence similarity to plant glycolate oxidase, a prototypical 2-hydroxy acid oxidase. The products of these...