(S)-2-Aminobutane-1,4-dithiol hydrochloride

(S)-2-Aminobutane-1,4-dithiol hydrochloride Structure
(S)-2-Aminobutane-1,4-dithiol hydrochloride structure
Common Name (S)-2-Aminobutane-1,4-dithiol hydrochloride
CAS Number 1363376-98-0 Molecular Weight 173.72800
Density N/A Boiling Point N/A
Molecular Formula C4H12ClNS2 Melting Point N/A
MSDS USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

A family of cationic polyamides for in vitro and in vivo gene transfection.

Acta Biomater. 22 , 120-30, (2015)

The purpose of this study is to develop biodegradable cationic polyamides for non-viral gene delivery and elucidate their structural effects on gene transfection activity. To this end, a group of novel cationic polyamides were synthesized by polycondensation ...

Chemical de-conjugation for investigating the stability of small molecule drugs in antibody-drug conjugates.

J. Pharm. Biomed. Anal. 117 , 304-10, (2015)

Antibody-drug conjugates (ADCs) offer new therapeutic options for advanced cancer patients through precision killing with fewer side effects. The stability and efficacy of ADCs are closely related, emphasizing the urgency and importance of gaining a comprehen...

Catalysis by the tumor-suppressor enzymes PTEN and PTEN-L.

PLoS ONE 10(1) , e0116898, (2015)

Phosphatase and tensin homologue deleted from chromosome ten (PTEN) is a lipid phosphatase tumor suppressor that is lost or inactivated in most human tumors. The enzyme catalyzes the hydrolysis of phosphatidylinositol-(3,4,5)-trisphosphate (PIP3) to form phos...