Collagen

Collagen Structure
Collagen structure
Common Name Collagen
CAS Number 9007-34-5 Molecular Weight 300.354
Density 1.4±0.1 g/cm3 Boiling Point 558.2±60.0 °C at 760 mmHg
Molecular Formula C13H24N4O4 Melting Point N/A
MSDS USA Flash Point 291.4±32.9 °C

DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity.

J. Exp. Med. 211(13) , 2549-66, (2014)

DOCK8 mutations result in an inherited combined immunodeficiency characterized by increased susceptibility to skin and other infections. We show that when DOCK8-deficient T and NK cells migrate through confined spaces, they develop cell shape and nuclear defo...

Tissue-specific splice variants of HARE/Stabilin-2 are expressed in bone marrow, lymph node, and spleen.

Biochem. Biophys. Res. Commun. 456(1) , 257-61, (2015)

The hyaluronan receptor for endocytosis (HARE), or Stabilin-2, is the mammalian endocytic clearance receptor for HA, heparin, advanced glycation end-products, acetylated and oxidized low-density lipoproteins and collagen N-terminal propeptides. This large 255...

Gelatin hydrogel as a carrier of recombinant human fibroblast growth factor-2 during rat mandibular distraction.

J. Oral Maxillofac. Surg. 72(10) , 2015-31, (2014)

The aim of the present study was to evaluate the feasibility of a gelatin hydrogel system to enhance recombinant human fibroblast growth factor-2 (rhFGF-2)-induced osteogenic effects during rat mandibular distraction.Mandibular distraction was performed in 28...

Preparation and characterization of gelatin from collagen biomass obtained through a pH-shifting process of mechanically separated turkey meat.

Poult. Sci. 93(4) , 989-1000, (2014)

Gelatins were extracted from mechanically separated turkey meat following 2 different approaches. The first method was based on a 2-stage batch extraction at 50 and 60°C, respectively, whereas the second method consisted of recovering gelatin from a collagen ...

Major surface protein LipL32 is not required for either acute or chronic infection with Leptospira interrogans.

Ann. Biomed. Eng. 41(10) , 2181-92, (2013)

Leptospira interrogans is responsible for leptospirosis, a zoonosis of worldwide distribution. LipL32 is the major outer membrane protein of pathogenic leptospires, accounting for up to 75% of total outer membrane protein. In recent times LipL32 has become th...

Combined hydrogels that switch human pluripotent stem cells from self-renewal to differentiation.

Proc. Natl. Acad. Sci. U. S. A. 111(15) , 5580-5, (2014)

The ability of materials to define the architecture and microenvironment experienced by cells provides new opportunities to direct the fate of human pluripotent stem cells (HPSCs) [Robinton DA, Daley GQ (2012) Nature 481(7381):295-305]. However, the condition...

Protein-polymer functionalized aqueous ferrofluids showing high T2 relaxivity.

J. Biomed. Nanotechnol. 10(5) , 811-9, (2014)

Controlled size, shape and dispersibility of superparamagnetic iron oxide nanoparticles (SPIONs), has been achieved in a protein-polymer colloidal dispersion. Stable ferrofluid (FF) is synthesized in an aqueous medium of collagen, bovine serum albumin and pol...

Estrogen inhibits mast cell chymase release to prevent pressure overload-induced adverse cardiac remodeling.

Hypertension 65(2) , 328-34, (2015)

Estrogen regulation of myocardial chymase and chymase effects on cardiac remodeling are unknown. To test the hypothesis that estrogen prevents pressure overload-induced adverse cardiac remodeling by inhibiting mast cell (MC) chymase release, transverse aortic...

Slow-releasing rapamycin-coated bionic peripheral nerve scaffold promotes the regeneration of rat sciatic nerve after injury.

Life Sci. 122 , 92-9, (2015)

To investigate the effect of locally slow-released rapamycin (RAPA) from the bionic peripheral nerve scaffold on rat sciatic nerve regeneration in the early phase of nerve injury.Slow-releasing RAPA-polyhydroxy alcohol (PLGA) microspheres were prepared and te...

Novel thrombolytic protease from edible and medicinal plant Aster yomena (Kitam.) Honda with anticoagulant activity: purification and partial characterization.

J. Biosci. Bioeng. 118(4) , 372-7, (2014)

A thrombolytic protease named kitamase possessing anticoagulant property was purified from edible and medicinal plant Aster yomena (Kitam.) Honda. Kitamase showed a molecular weight of 50 kDa by SDS-PAGE and displayed a strong fibrin zymogram lysis band corre...