Ethoxylated hydrogenated castor oil
Ethoxylated hydrogenated castor oil structure
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Common Name | Ethoxylated hydrogenated castor oil | ||
|---|---|---|---|---|
| CAS Number | 61788-85-0 | Molecular Weight | 375.864 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 529.0±50.0 °C at 760 mmHg | |
| Molecular Formula | C21H23ClFNO2 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 273.8±30.1 °C | |
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Formulation and biopharmaceutical evaluation of silymarin using SMEDDS.
Arch. Pharm. Res. 30(1) , 82-9, (2007) Silymarin has been used to treat hepatobiliary diseases. However, it has a low bioavailability after being administered orally on account of its low solubility in water. In order to improve the dissolution rate, silymarin was formulated in the form of a self-... |
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Preparation and evaluation of self-nanoemulsifying tablets of carvedilol.
AAPS PharmSciTech 10(1) , 183-92, (2009) The purpose of this study was to combine the advantages of self-nanoemulsifying drug delivery systems and tablets as a conventional dosage form emphasizing the excipients' effect on the development of a new dosage form. Systems composed of HCO-40, Transcutol ... |
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Detailed molecular characterization of castor oil ethoxylates by liquid chromatography multistage mass spectrometry.
J. Chromatogr. A. 1218(40) , 7166-72, (2011) The molecular characterization of castor oil ethoxylates (CASEOs) was studied by reverse-phase liquid chromatography (RPLC) mass spectrometry (MS) and multistage mass spectrometry (MS(n)). The developed RPLC method allowed the separation of the various CASEO ... |
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Effect of oxyethylene moieties in hydrogenated castor oil on the pharmacokinetics of menatetrenone incorporated in O/W lipid emulsions prepared with hydrogenated castor oil and soybean oil in rats.
J. Drug Target. 11(1) , 37-43, (2003) Lipid emulsions with particle sizes of 190-270 nm were prepared with soybean oil (SO) and a series of hydrogenated castor oils (HCOs) with various oxyethylene numbers, and the effect of oxyethylene numbers of HCOs on the pharmacokinetics of menatetrenone inco... |
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Polyoxyethylene hydrogenated castor oil modulates benzalkonium chloride toxicity: comparison of acute corneal barrier dysfunction induced by travoprost Z and travoprost.
J. Ocul. Pharmacol. Ther. 27(5) , 437-44, (2011) To determine the element that modulates benzalkonium chloride (BAC) toxicity by using a new electrophysiological method to evaluate acute corneal barrier dysfunction induced by travoprost Z with sofZia (Travatan Z(®)), travoprost with 0.015% BAC (Travatan(®))... |
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Formulation of parenteral microemulsion containing itraconazole.
Arch. Pharm. Res. 30(1) , 114-23, (2007) The aim of this study was to develop an aqueous parenteral formulation containing itraconazole (ITZ) using an o/w microemulsion system. A mixture of benzyl alcohol and medium chain triglyceride (3/1) was chosen as the oil phase. Pseudoternary phase diagrams o... |
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Polyoxyl 60 hydrogenated castor oil free nanosomal formulation of immunosuppressant Tacrolimus: pharmacokinetics, safety, and tolerability in rodents and humans.
Int. Immunopharmacol. 10(3) , 325-30, (2010) Develop Nanosomal formulation of Tacrolimus to provide safer alternative treatment for organ transplantation patients. Investigate safety, tolerability and pharmacokinetics of Nanosomal Tacrolimus formulation versus marketed Tacrolimus containing polyoxyl 60 ... |
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Improving tenoxicam solubility and bioavailability by cosolvent system.
AAPS PharmSciTech 10(1) , 166-71, (2009) The formulation study of tenoxicam, a poorly water-soluble drug, was developed by use of a ternary cosolvent system and has significantly enhanced the solubility. Additionally, the relative bioavailability of testing formulation was also evaluated by New Zeal... |
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Absorption of interferon alpha from patches in rats.
J. Drug Target. 13(6) , 383-90, (2005) Interferon alpha (IFN-alpha), patch preparations composed of three layers, water-insoluble backing layer, drug containing layer with absorption enhancer and surface layer containing pH-dependent polymer were prepared. As absorption enhancer, three surfactants... |
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Spin-probe investigations of head group behavior in aqueous dispersions of a nonionic amphiphilic compound.
Lipids 42(5) , 457-62, (2007) Head group behavior of nonionic amphiphilic compound, (poly(oxyethylene) hydrogenated castor oil, HCO), in aqueous dispersions were investigated by EPR (electron paramagnetic resonance) in conjunction with a modern slow-tumbling simulation. The aliphatic spin... |