Hydroxyethyl starch
Hydroxyethyl starch structure
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Common Name | Hydroxyethyl starch | ||
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| CAS Number | 9005-27-0 | Molecular Weight | 580.575 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H44O17 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Uncontrolled hemorrhagic shock results in a hypercoagulable state modulated by initial fluid resuscitation regimens.
J. Trauma Acute Care Surg. 75(1) , 129-34, (2013) Previous studies have shown large-volume resuscitation modulates coagulopathy and inflammation. Our objective was to analyze the effects of initial bolus fluids used in military and civilian settings on coagulation and inflammation in a prospective, randomize... |
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Time to assess alternatives to hydroxyethyl starch to use instead of 0.9% saline in fluid replacement.
BMJ 347 , f4651, (2013)
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Physiological levels of A-, B- and C-type natriuretic peptide shed the endothelial glycocalyx and enhance vascular permeability.
Basic Res. Cardiol. 108(3) , 347, (2013) Atrial natriuretic peptide (ANP) is a peptide hormone released from the cardiac atria during hypervolemia. Though named for its well-known renal effect, ANP has been demonstrated to acutely increase vascular permeability in vivo. Experimentally, this phenomen... |
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Europe recommends ban on common plasma substitute.
BMJ 346 , f3942, (2013)
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Meta-analyses of hydroxyethyl starch for volume resuscitation.
JAMA 309(21) , 2209, (2013)
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Starch safety in resuscitation - when will we ever learn?
S. Afr. Med. J. 103(6) , 365-7, (2013) Recent trials have failed to demonstrate a survival benefit from the use of hydroxyethyl starches (HES) as a colloid in fluid resuscitation and have raised concerns of renal harm. In severe sepsis, there is a concerning signal of increased mortality. New high... |
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Is 6% tetrastarch 130kDa (hydroxyethyl starch 130/0.4 or 130/0.42) suitable for severe sepsis?
Br. J. Hosp. Med. (Lond.) 74(3) , 178, (2013)
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Is it the end of the road for synthetic starches in critical illness? No place for hydroxyethyl starch solutions in treatment of patients with sepsis.
BMJ 346 , f1805, (2013)
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NHS should ban use of starch based intravenous fluids, say researchers.
BMJ 346 , f1323, (2013)
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Impact of fluid infusion rate on restoring plasma volume in sepsis.
Crit. Care Med. 41(3) , 931-2, (2013)
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