Iron dextran
Iron dextran structure
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Common Name | Iron dextran | ||
|---|---|---|---|---|
| CAS Number | 9004-66-4 | Molecular Weight | 1347.364 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | H2O4S.Fe | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
| Symbol |
GHS07, GHS08 |
Signal Word | Danger | |
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Deferasirox shows in vitro and in vivo antileukemic effects on murine leukemic cell lines regardless of iron status
Exp. Hematol. 41(6) , 539-46, (2013) Numerous studies have shown the antiproliferative effect of iron chelating agents (ICAs), which have been used traditionally in patients with secondary iron overload (SIO). Because the in vivo model for these studies has been animals with normal iron status, ... |
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[Importance of the different i.v. iron generations for everyday medical practice].
MMW Fortschr. Med. 155 Suppl 1 , 18-24, (2013) Iron deficiency and anaemia occur in particular in women or as comorbid conditions to a varietyof chronic diseases. Besides oral preparations, parenteral iron therapies are also available for the treatment of iron deficiency or anaemia. In the light of the gr... |
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Use of intravenous iron supplementation in chronic kidney disease: an update.
Iran. J. Kidney Dis. 7(1) , 9-22, (2013) Iron deficiency is an important clinical concern in chronic kidney disease (CKD), giving rise to iron-deficiency anemia and impaired cellular function. Oral supplementation, in particular with ferrous salts, is associated with a high rate of gastrointestinal ... |
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[Safety aspects of parenteral iron supplementation therapies in patients with chronic kidney disease].
Dtsch. Med. Wochenschr. 138(24) , 1312-7, (2013) Iron deficiency often occurs in patients with chronic kidney disease and can be effectively treated with parenteral supplementation of iron. In these patients, prompt application of iron therapy can help to reduce the dependence of erythropoietin-stimulating ... |
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Iron dextran treatment does not induce serum protein carbonyls in the newborn pig.
Animal 6(1) , 79-86, (2012) Oxidation of serum proteins can lead to carbonyl formation that alters their function and is often associated with stress-related diseases. As it is recommended that all pigs reared in modern production facilities be given supplemental iron at birth to preven... |
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Total dose iron dextran infusion in cancer patients: is it SaFe2+?
J. Natl. Compr. Canc. Netw. 10(5) , 669-76, (2012) The feasibility of the large, single-dose intravenous iron repletion method, which is known today as total dose infusion (TDI), has been demonstrated over decades. However, this method of iron repletion was chiefly developed for patients with large iron defic... |
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Nifedipine prevents iron accumulation and reverses iron-overload-induced dopamine neuron degeneration in the substantia nigra of rats.
Neurotox. Res. 22(4) , 274-9, (2012) The mechanisms of iron accumulation in substantia nigra (SN) of Parkinson's diseases remain unclear. The objective of this study was to investigate effects of nifedipine on iron-overload-induced iron accumulation and neurodegeneration in SN of rats. By high p... |
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Minimally invasive transdermal delivery of iron-dextran.
J. Pharm. Sci. 102(3) , 987-93, (2013) Iron deficiency is one of the most prevalent and serious health issues among people all over the world. Iron-dextran (ID) colloidal solution is one among the very few US Food and Drug Administration (FDA)-approved iron sources for parenteral administration of... |
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The C57BL/6 genetic background confers cardioprotection in iron-overloaded mice.
Blood Transfus. 11(1) , 88-93, (2013) Chronic transfusion therapy causes a progressive iron overload that damages many organs including the heart. Recent evidence suggests that L-type calcium channels play an important role in iron uptake by cardiomyocytes under conditions of iron overload. Given... |
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Spondias pinnata stem bark extract lessens iron overloaded liver toxicity due to hemosiderosis in Swiss albino mice.
Ann. Hepatol. 12(1) , 123-9, (2013) The present study was designed to evaluate the ameliorating effect of 70% methanol extract of Spondias pinnata (SPME) on iron overload induced liver injury. Iron overload was induced by intraperitoneal administration of iron-dextran into mice and resulting li... |