catechol o-methyltransferase
catechol o-methyltransferase structure
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Common Name | catechol o-methyltransferase | ||
|---|---|---|---|---|
| CAS Number | 9012-25-3 | Molecular Weight | 636.942 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 771.4±40.0 °C at 760 mmHg | |
| Molecular Formula | C38H68O7 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 227.5±20.8 °C | |
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Initial characterization of the human central proteome.
BMC Syst. Biol. 5 , 17, (2011) On the basis of large proteomics datasets measured from seven human cell lines we consider their intersection as an approximation of the human central proteome, which is the set of proteins ubiquitously expressed in all human cells. Composition and properties... |
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Complete sequencing and characterization of 21,243 full-length human cDNAs.
Nat. Genet. 36 , 40-5, (2004) As a base for human transcriptome and functional genomics, we created the "full-length long Japan" (FLJ) collection of sequenced human cDNAs. We determined the entire sequence of 21,243 selected clones and found that 14,490 cDNAs (10,897 clusters) were unique... |
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The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res. 14 , 2121-7, (2004) The National Institutes of Health's Mammalian Gene Collection (MGC) project was designed to generate and sequence a publicly accessible cDNA resource containing a complete open reading frame (ORF) for every human and mouse gene. The project initially used a r... |
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Characterization of single-nucleotide polymorphisms in coding regions of human genes.
Nat. Genet. 22(3) , 231-8, (1999) A major goal in human genetics is to understand the role of common genetic variants in susceptibility to common diseases. This will require characterizing the nature of gene variation in human populations, assembling an extensive catalogue of single-nucleotid... |
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Large-scale cDNA transfection screening for genes related to cancer development and progression.
Proc. Natl. Acad. Sci. U. S. A. 101(44) , 15724-9, (2004) A large-scale assay was performed by transfecting 29,910 individual cDNA clones derived from human placenta, fetus, and normal liver tissues into human hepatoma cells and 22,926 cDNA clones into mouse NIH 3T3 cells. Based on the results of colony formation in... |
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A genome annotation-driven approach to cloning the human ORFeome.
Genome Biol. 5(10) , R84, (2004) We have developed a systematic approach to generating cDNA clones containing full-length open reading frames (ORFs), exploiting knowledge of gene structure from genomic sequence. Each ORF was amplified by PCR from a pool of primary cDNAs, cloned and confirmed... |
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The DNA sequence of human chromosome 22.
Nature 402(6761) , 489-95, (1999) Knowledge of the complete genomic DNA sequence of an organism allows a systematic approach to defining its genetic components. The genomic sequence provides access to the complete structures of all genes, including those without known function, their control ... |
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Human chromosome 11 DNA sequence and analysis including novel gene identification.
Nature 440(7083) , 497-500, (2006) Chromosome 11, although average in size, is one of the most gene- and disease-rich chromosomes in the human genome. Initial gene annotation indicates an average gene density of 11.6 genes per megabase, including 1,524 protein-coding genes, some of which were ... |
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Low dopamine function in attention deficit/hyperactivity disorder: should genotyping signify early diagnosis in children?
Postgrad. Med. 126(1) , 153-77, (2014) Attention deficit/hyperactivity disorder (ADHD) is present in 8% to 12% of children, and 4% of adults worldwide. Children with ADHD can have learning impairments, poor selfesteem, social dysfunction, and an increased risk of substance abuse, including cigaret... |
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The role of catechol-O-methyltransferase in catechol-enhanced erythroid differentiation of K562 cells.
Toxicol. Appl. Pharmacol. 273(3) , 635-43, (2013) Catechol is widely used in pharmaceutical and chemical industries. Catechol is also one of phenolic metabolites of benzene in vivo. Our previous study showed that catechol improved erythroid differentiation potency of K562 cells, which was associated with dec... |