carboxypeptidase w
carboxypeptidase w structure
|
Common Name | carboxypeptidase w | ||
|---|---|---|---|---|
| CAS Number | 9046-67-7 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
| Symbol |
GHS07, GHS08 |
Signal Word | Danger | |
|
Benzoylation and sinapoylation of glucosinolate R-groups in Arabidopsis.
Plant J. 72(3) , 411-22, (2012) Glucosinolates (GSLs) are nitrogen- and sulfur-containing metabolites that contribute to human health and plant defense. The biological activities of these molecules are largely dependent on modification of the GSL R-groups derived from their corresponding am... |
|
|
Role of cathepsin A and cathepsin C in the regulation of glycosidase activity.
Folia Histochem. Cytobiol. 50(1) , 20-4, (2012) Increased tissue activity of cathepsin A and cathepsin C can be observed in many pathological conditions. It is associated with an enhanced degradation of glycosaminoglycans, proteoglycans, and glycoproteins, and results in their decreased tissue content. Cat... |
|
|
Mechanism for effective lymphoid cell and tissue loading following oral administration of nucleotide prodrug GS-7340.
Mol. Pharm. 10(2) , 459-66, (2013) GS-7340 is a prodrug of tenofovir (TFV) that more efficiently delivers TFV into lymphoid cells and tissues than the clinically used prodrug TFV disoproxil fumarate, resulting in higher antiviral potency at greatly reduced doses and lower systemic TFV exposure... |
|
|
Relative quantitation of peptides in wild-type and Cpe(fat/fat) mouse pituitary using stable isotopic tags and mass spectrometry.
J. Mass Spectrom. 40(2) , 227-37, (2005) Cpe(fat/fat) mice have a point mutation in the coding region of the carboxypeptidase E gene that renders the enzyme inactive. As a result, these mice have reduced levels of several neuropeptides and greatly increased levels of the peptide processing intermedi... |
|
|
End-binding proteins and Ase1/PRC1 define local functionality of structurally distinct parts of the microtubule cytoskeleton.
Trends Cell Biol. 23(2) , 54-63, (2013) The microtubule cytoskeleton is crucial for the intracellular organization of eukaryotic cells. It is a dynamic scaffold that has to perform a variety of very different functions. This multitasking is achieved through the activity of numerous microtubule-asso... |
|
|
Identification of interaction site of propeptide toward mature carboxypeptidase Y (mCPY) based on the similarity between propeptide and CPY inhibitor (IC).
Biosci. Biotechnol. Biochem. 76(1) , 153-6, (2012) Both the propeptide in the precursor carboxypeptidase Y (proCPY) and the mature CPY (mCPY)-specific endogenous inhibitor (I(C)) inhibit CPY activity. The N-terminal inhibitory reactive site of I(C) (the N-terminal seven amino acids of I(C)) binds to the subst... |
|
|
Simultaneous screening of multiple mutations by invader assay improves molecular diagnosis of hereditary hearing loss: a multicenter study.
PLoS ONE 7(2) , e31276, (2012) Although etiological studies have shown genetic disorders to be a common cause of congenital/early-onset sensorineural hearing loss, there have been no detailed multicenter studies based on genetic testing. In the present report, 264 Japanese patients with bi... |
|
|
A pro-cathepsin L mutant is a luminal substrate for endoplasmic-reticulum-associated degradation in C. elegans.
PLoS ONE 7(7) , e40145, (2012) Endoplasmic-reticulum associated degradation (ERAD) is a major cellular misfolded protein disposal pathway that is well conserved from yeast to mammals. In yeast, a mutant of carboxypeptidase Y (CPY*) was found to be a luminal ER substrate and has served as a... |
|
|
Effects on vesicular transport pathways at the late endosome in cells with limited very long-chain fatty acids.
J. Lipid Res. 54(3) , 831-42, (2013) Very long-chain fatty acids (VLCFAs), fatty acids with chain-length greater than 20 carbons, possess a wide range of biological functions. However, their roles at the molecular level remain largely unknown. In the present study, we screened for multicopy supp... |
|
|
Steroid signaling in plants: from the cell surface to the nucleus.
Bioessays 23(11) , 1028-36, (2001) Steroid hormones are signaling molecules important for normal growth, development and differentiation of multicellular organisms. Brassinosteroids (BRs) are a class of polyhydroxylated steroids that are necessary for plant development. Molecular genetic studi... |