5-Fluoro-2-methylbenzoic acid
5-Fluoro-2-methylbenzoic acid structure
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Common Name | 5-Fluoro-2-methylbenzoic acid | ||
|---|---|---|---|---|
| CAS Number | 33184-16-6 | Molecular Weight | 154.138 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 262.1±20.0 °C at 760 mmHg | |
| Molecular Formula | C8H7FO2 | Melting Point | 130-132 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 112.3±21.8 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Multkilogram Scale-Up of a Reductive Alkylation Route to a Novel PARP Inhibitor. Gillmore AT, et al.
Org. Process Res. Dev. 16(12) , 2063-72, (1999)
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Design of HIV-1 integrase inhibitors targeting the catalytic domain as well as its interaction with LEDGF/p75: a scaffold hopping approach using salicylate and catechol groups.
Bioorg. Med. Chem. 19 , 4935, (2011) HIV-1 integrase (IN) is a validated therapeutic target for antiviral drug design. However, the emergence of viral strains resistant to clinically studied IN inhibitors demands the discovery of novel inhibitors that are structurally as well mechanistically dif... |
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Structure-activity relationship of HIV-1 protease inhibitors containing alpha-hydroxy-beta-amino acids. Detailed study of P1 site.
Bioorg. Med. Chem. 7(9) , 2063-72, (1999) The structure-activity relationship of HIV-1 protease (HIV-1 PR) inhibitors containing alpha-hydroxy-beta-amino acids is discussed. We demonstrated that substituent groups on the P1 aromatic rings of the inhibitors exert significant influence on their biologi... |