4-Methyl-1-piperazinecarbonyl chloride hydrochloride

4-Methyl-1-piperazinecarbonyl chloride hydrochloride Structure
4-Methyl-1-piperazinecarbonyl chloride hydrochloride structure
Common Name 4-Methyl-1-piperazinecarbonyl chloride hydrochloride
CAS Number 55112-42-0 Molecular Weight 199.078
Density N/A Boiling Point 247.5ºC at 760 mmHg
Molecular Formula C6H12Cl2N2O Melting Point 225-228 °C(lit.)
MSDS Chinese USA Flash Point 103.5ºC
Symbol GHS05
GHS05
Signal Word Danger

Design, synthesis, and in vitro and in vivo biological studies of a 3'-deoxythymidine conjugate that potentially kills cancer cells selectively.

PLoS ONE 7(12) , e52199, (2012)

Thymidine kinases (TKs) have been considered one of the potential targets for anticancer therapeutic because of their elevated expressions in cancer cells. However, nucleobase analogs targeting TKs have shown poor selective cytotoxicity in cancer cells despit...

Fluorescent diethylcarbamazine analogues: sites of accumulation in Brugia malayi.

Bioconjug. Chem. 18(6) , 1818-23, (2007)

New fluorescein and rhodamine B-labeled antifilarial drug DEC analogues for use in drug localization studies with confocal microscopy have been prepared by a high-yield three-step synthesis. The resulting beta-amine-substituted DEC analogue has a single ethyl...

Brown DJ.

The Chemistry of Heterocyclic Compounds , (2003), 317