heptan-1,7-diamin

heptan-1,7-diamin Structure
heptan-1,7-diamin structure
Common Name heptan-1,7-diamin
CAS Number 646-19-5 Molecular Weight 130.231
Density 0.9±0.1 g/cm3 Boiling Point 224.0±8.0 °C at 760 mmHg
Molecular Formula C7H18N2 Melting Point 26-29 °C(lit.)
MSDS USA Flash Point 87.8±0.0 °C
Symbol GHS05
GHS05
Signal Word Danger

In vitro inhibition of lysine decarboxylase activity by organophosphate esters.

Biochem. Pharmacol. 92(3) , 506-16, (2014)

Organophosphate esters (OPEs), a major group of organophosphorus flame retardants, are regarded as emerging environmental contaminants of health concern. Amino acid decarboxylases catalyze the conversion of amino acids into polyamines that are essential for c...

Self-immolative polycations as gene delivery vectors and prodrugs targeting polyamine metabolism in cancer.

Mol. Pharm. 12(2) , 332-41, (2015)

Polycations are explored as carriers to deliver therapeutic nucleic acids. Polycations are conventionally pharmacological inert with the sole function of delivering therapeutic cargo. This study reports synthesis of a self-immolative polycation (DSS-BEN) base...

Antitubercular activity of alpha,omega-diaminoalkanes, H2N(CH2)nNH2.

Bioorg. Med. Chem. Lett. 19 , 4937-8, (2009)

A series of 11 alpha,omega-diaminoalkanes, (H(2)N(CH(2))(n)NH(2), n=2-12) have been evaluated for their in vitro antibacterial activity against Mycobacterium tuberculosis H37Rv. Compounds, (H(2)N(CH(2))(n)NH(2), n=9-12), exhibited a very good activities in th...

A label-free impedimetric immunosensor for direct determination of the textile dye Disperse Orange 1.

Talanta 142 , 183-9, (2015)

A strategy for a label-free impedimetric immunosensor is described for detection of the textile dye Disperse Orange 1 (DO1). The compounds 1,12-diaminododecane (DADD) and then 1,7-diaminoheptane (DAH) were firstly successively grafted onto a glassy carbon ele...

Density of Trap States and Auger-mediated Electron Trapping in CdTe Quantum-Dot Solids.

Nano Lett. 15 , 3056-66, (2015)

Charge trapping is an ubiquitous process in colloidal quantum-dot solids and a major limitation to the efficiency of quantum dot based devices such as solar cells, LEDs, and thermoelectrics. Although empirical approaches led to a reduction of trapping and the...

Underivatized polyamine analysis in plant samples by ion pair LC coupled with electrospray tandem mass spectrometry.

Plant Physiol. Biochem. 47(7) , 592-8, (2009)

Polyamines are key regulators of cell development and many plant responses to environmental challenges, however, their functions still remain unclear in complex interactions with other hormones and in biotic or abiotic stress. This lack of knowledge derives f...

Effect of drugs inhibiting spermidine biosynthesis and metabolism on the in vitro development of Plasmodium falciparum.

Parasitol. Res. 87(11) , 963-72, (2001)

Treatment of Plasmodium falciparum with the potent inhibitor dicyclohexylamine completely arrests in vitro cell proliferation of the chloroquine-susceptible P. falciparum strain NF54 and the R strain, which shows less sensivity to chloroquine. The average inh...

Regulation of the polyamine metabolic pathway in the endometrium of cows during early diestrus.

Mol. Reprod. Dev. 81(7) , 584-94, (2014)

The timing and magnitude of exposure to preovulatory estradiol followed by post-ovulatory progesterone (periovulatory endocrine milieu) in cattle modulate endometrial gene expression, histotroph composition, and conceptus development, but the mechanisms under...

Occurrence of polyamines in root nodules of Phaseolus vulgaris in symbiosis with Rhizobium tropici in response to salt stress

Phytochemistry 107 , 32-41, (2014)

The level and variety of polyamines is higher in root nodules of Phaseolus vulgaris compared to leaves and roots. UPLC-mass spectrometry analysis revealed the presence of the uncommon polyamine 4-aminobutylcadaverine that seems to be involved in the response ...

Modification of eukaryotic initiation factor 5A from Plasmodium vivax by a truncated deoxyhypusine synthase from Plasmodium falciparum: An enzyme with dual enzymatic properties.

Bioorg. Med. Chem. 15 , 6200-7, (2007)

The increasing resistance of the malaria parasites enforces alternative directions in finding new drug targets. Present findings from the malaria parasite Plasmodium vivax, causing tertiary malaria, suggest eukaryotic initiation factor 5A (eIF-5A) to be a pro...