Aminoguanidine hydrochloride
Aminoguanidine hydrochloride structure
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Common Name | Aminoguanidine hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 1937-19-5 | Molecular Weight | 110.546 | |
| Density | N/A | Boiling Point | 261.4ºC at 760 mmHg | |
| Molecular Formula | CH7ClN4 | Melting Point | 162-166 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 111.9ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival.
J. Pathol. 235(4) , 581-92, (2015) Biomechanical strain imposed by age-related thickening of the basal lamina and augmented tissue stiffness in the prostate gland coincides with increased cancer risk. Here we hypothesized that the structural alterations in the basal lamina associated with age ... |
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Structure elucidation of secondary metabolites isolated from the leaves of Ixora undulate and their inhibitory activity toward advanced glycation end-products formation.
Phytochemistry 108 , 189-95, (2014) Three aromatic glycosides (1-3), two sulfur and nitrogen-containing compound glucosides (4, 5), and one flavonoid glycoside (6) were isolated from the leaves of Ixora undulata. Their structures were established by extensive 1D, 2D NMR, and HRESIMS experiments... |
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Vicenin 2 isolated from Artemisia capillaris exhibited potent anti-glycation properties.
Food Chem. Toxicol. 69 , 55-62, (2014) Vicenin 2, isolated from a traditionally used medicinal plant Artemisia capillaris, is a 6,8-di-C-glucoside of apigenin which has been previously reported to possess a wide variety of pharmacological activities including antioxidant, anti-inflammatory, anti-c... |
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Two new flavones from Salvia plebeia.
Nat. Prod. Res. 29 , 1315-22, (2015) Two new flavones neocafhispidulin (1) and 6″-O-acetyl homoplantaginin (2), together with 10 known flavones and 1 polyphenol were isolated from the whole plants of Salvia plebeia. R. Br. Compounds 3 and 4 were reported from this plant for the first time. Their... |
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Nitric oxide boosts TLR-4 mediated lipocalin 2 expression in chondrocytes.
J. Orthop. Res. 31(7) , 1046-52, (2013) Lipocalin 2 (LCN2) has recently emerged as a novel adipokine involved in different processes including arthritis and chondrocyte inflammatory response. However, little is known about its activity on chondrocyte homeostasis and its regulation by nitric oxide (... |
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The stimulated innate resistance event in Bordetella pertussis infection is dependent on reactive oxygen species production.
Infect. Immun. 81(7) , 2371-8, (2013) The exacerbated induction of innate immune responses in airways can abrogate diverse lung infections by a phenomenon known as stimulated innate resistance (StIR). We recently demonstrated that the enhancement of innate response activation can efficiently impa... |
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Intracellular accumulation of advanced glycation end products induces apoptosis via endoplasmic reticulum stress in chondrocytes.
FEBS J. 280(7) , 1617-29, (2013) Mammalian cells attempt to maintain their homeostasis under endoplasmic reticulum (ER) stress. If the stress cannot be alleviated, cells are led to apoptosis through induction of C/EBP homologous protein (CHOP). ER stress is provoked in osteoarthritis chondro... |
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Antidepressant-like activity of ellagic acid in unstressed and acute immobilization-induced stressed mice.
Pharmacol. Rep. 64(4) , 796-807, (2012) The aim of present study was to evaluate antidepressant-like activity of ellagic acid in Swiss young male albino mice; and to explore the possible underlying mechanisms for this activity.Mice were immobilized for 150 min once only for induction of stress. Ell... |
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Promising anti-diabetic potential of capillin and capillinol isolated from Artemisia capillaris.
Arch. Pharm. Res. 39 , 340-9, (2016) Caffeoylquinic acids, flavonoids, and coumarins isolated from Artemisia capillaris have recently emerged as therapeutic candidates for diabetes and diabetic complications; however, there have been very few studies of the anti-diabetic potential of polyacetyle... |
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iNOS expression and osteocyte apoptosis in idiopathic, non-traumatic osteonecrosis.
Acta Orthop. 86(1) , 134-41, (2015) Non-traumatic osteonecrosis is a progressive disease with multiple etiologies. It affects younger individuals more and more, often leading to total hip arthroplasty. We investigated whether there is a correlation between inducible nitric oxide synthase (iNOS)... |