NSC-632839

NSC-632839 Structure
NSC-632839 structure
Common Name NSC-632839
CAS Number 157654-67-6 Molecular Weight 339.858
Density N/A Boiling Point 522.7ºC at 760 mmHg
Molecular Formula C21H22ClNO Melting Point N/A
MSDS Chinese USA Flash Point 184ºC
Symbol GHS07
GHS07
Signal Word Warning

Palmitoleate Reverses High Fat-induced Proinflammatory Macrophage Polarization via AMP-activated Protein Kinase (AMPK).

J. Biol. Chem. 290 , 16979-88, (2015)

A rise in tissue-embedded macrophages displaying "M1-like" proinflammatory polarization is a hallmark of metabolic inflammation during a high fat diet or obesity. Here we show that bone marrow-derived macrophages (BMDM) from high fat-fed mice retain a memory ...

Synthesis, evaluation and molecular docking studies of amino acid derived N-glycoconjugates as antibacterial agents.

Bioorg. Chem. 63 , 110-5, (2015)

Six amino acid derived N-glycoconjugates of d-glucose were synthesized, characterized and tested for antibacterial activity against G(+)ve (Bacillus cereus) as well as G(-)ve (Escherichia coli and Klebsiella pneumoniae) bacterial strains. All the tested compo...

In vitro-in vivo evaluation of lipid based formulations of the CETP inhibitors CP-529,414 (torcetrapib) and CP-532,623.

Eur. J. Pharm. Biopharm. 88(3) , 973-85, (2014)

The present study investigated the use of lipid based drug delivery systems to enhance the oral bioavailability of the CETP inhibitors CP-532,623 and torcetrapib. A series of self-emulsifying lipid based drug delivery systems (SEDDS) were assembled and examin...

CD200: association with cancer stem cell features and response to chemoradiation in head and neck squamous cell carcinoma.

Head Neck 37(3) , 327-35, (2015)

The purpose of this study was to characterize the expression of CD200, a membrane protein that functions in immune evasion, to examine its correlations with cancer stem cell (CSC)-like features and analyze its response to chemotherapy and radiation in human p...

Polycomb Repressor Complex 1 Member, BMI1 Contributes to Urothelial Tumorigenesis through p16-Independent Mechanisms.

Transl. Oncol. 8 , 387-99, (2015)

Urothelial carcinoma (UC) causes significant morbidity and remains the most expensive cancer to treat because of the need for repeated resections and lifelong monitoring for patients with non-muscle-invasive bladder cancer (NMIBC). Novel therapeutics and stra...

Cross reactive molecules of human lymphatic filaria Brugia malayi inhibit Leishmania donovani infection in hamsters.

Acta Trop. 152 , 103-11, (2015)

Coinfections are common in natural populations and the outcome of their interactions depends on the immune responses of the host elicited by the parasites. Earlier we showed that immunization with BmAFII (Sephadex G-200 eluted) fraction of human lymphatic fil...

Formulation and in vitro, in vivo evaluation of effervescent floating sustained-release imatinib mesylate tablet.

PLoS ONE 10 , e0126874, (2015)

Imatinib mesylate is an antineoplastic agent which has high absorption in the upper part of the gastrointestinal tract (GIT). Conventional imatinib mesylate (Gleevec) tablets produce rapid and relatively high peak blood levels and requires frequent administra...

Platelet-derived growth factors and receptors in Canine Lymphoma.

J. Comp. Pathol. 151(4) , 322-8, (2014)

Platelet-derived growth factors (PDGFs) belong to a family of polypeptide growth factors that signal through cell surface tyrosine kinase receptors to stimulate growth, proliferation and differentiation. Platelet-derived growth factor receptors (PDGFRs) are a...

Western white pine SNP discovery and high-throughput genotyping for breeding and conservation applications.

BMC Plant Biol. 14 , 380, (2015)

Western white pine (WWP, Pinus monticola Douglas ex D. Don) is of high interest in forest breeding and conservation because of its high susceptibility to the invasive disease white pine blister rust (WPBR, caused by the fungus Cronartium ribicola J. C. Fisch)...

Tomato response traits to pathogenic Pseudomonas species: Does nitrogen limitation matter?

Plant Sci. 244 , 57-67, (2016)

Induced chemical defence is a cost-efficient protective strategy, whereby plants induce the biosynthesis of defence-related compounds only in the case of pest attack. Plant responses that are pathogen specific lower the cost of defence, compared to constituti...