![]() Strychnidin-10-one hydrochloride (1:1) structure
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Common Name | Strychnidin-10-one hydrochloride (1:1) | ||
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CAS Number | 1421-86-9 | Molecular Weight | 370.872 | |
Density | N/A | Boiling Point | 559.9ºC at 760mmHg | |
Molecular Formula | C21H23ClN2O2 | Melting Point | 295 °C | |
MSDS | Chinese USA | Flash Point | 292.4ºC | |
Symbol |
![]() ![]() GHS06, GHS09 |
Signal Word | Danger |
Parallel ON and OFF cone bipolar inputs establish spatially coextensive receptive field structure of blue-yellow ganglion cells in primate retina.
J. Mol. Endocrinol. 29 , 8372-87, (2009) In the primate retina the small bistratified, "blue-yellow" color-opponent ganglion cell receives parallel ON-depolarizing and OFF-hyperpolarizing inputs from short (S)-wavelength sensitive and combined long (L)- and middle (M)-wavelength sensitive cone photo... |
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Phosphocholine-Modified Macromolecules and Canonical Nicotinic Agonists Inhibit ATP-Induced IL-1β Release.
J. Immunol. 195 , 2325-34, (2015) IL-1β is a potent proinflammatory cytokine of the innate immune system that is involved in host defense against infection. However, increased production of IL-1β plays a pathogenic role in various inflammatory diseases, such as rheumatoid arthritis, gout, sep... |
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Inhibitory Interneurons That Express GFP in the PrP-GFP Mouse Spinal Cord Are Morphologically Heterogeneous, Innervated by Several Classes of Primary Afferent and Include Lamina I Projection Neurons among Their Postsynaptic Targets.
J. Neurosci. 35 , 7626-42, (2015) The superficial dorsal horn of the spinal cord contains numerous inhibitory interneurons, which regulate the transmission of information perceived as touch, pain, or itch. Despite the importance of these cells, our understanding of their roles in the neuronal... |
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Glycine transporter-1 controls nonsynaptic inhibitory actions of glycine receptors in the neonatal rat hippocampus.
J. Neurosci. 34(30) , 10003-9, (2014) Although functional glycinergic synapses have not been identified in the hippocampus, neurons in this area express Cl(-) permeable extrasynaptic glycine receptors (GlyRs). In experiments on CA3 pyramidal neurons on postnatal day 0-6 rat hippocampal slices, we... |
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Horizontal cell feedback without cone type-selective inhibition mediates "red-green" color opponency in midget ganglion cells of the primate retina.
J. Neurosci. 31 , 1762-72, (2011) The distinctive red-green dimension of human and nonhuman primate color perception arose relatively recently in the primate lineage with the appearance of separate long (L) and middle (M) wavelength-sensitive cone photoreceptor types. "Midget" ganglion cells ... |
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Local inhibition shapes duration tuning in the inferior colliculus of guinea pigs.
Hear. Res. 237 , 32-48, (2008) Neural tuning to sound durations is a useful filter for the identification of a variety of sounds. Previous studies have shown that the interaction between excitatory and inhibitory inputs plays a role in duration selectivity in echolocating bats. However, th... |
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Y-cell receptive field and collicular projection of parasol ganglion cells in macaque monkey retina.
J. Mol. Endocrinol. 28 , 11277-91, (2008) The distinctive parasol ganglion cell of the primate retina transmits a transient, spectrally nonopponent signal to the magnocellular layers of the lateral geniculate nucleus. Parasol cells show well-recognized parallels with the alpha-Y cell of other mammals... |
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Astrocyte-neuron interaction in the substantia gelatinosa of the spinal cord dorsal horn via P2X7 receptor-mediated release of glutamate and reactive oxygen species.
Glia 62(10) , 1671-86, (2014) The substantia gelatinosa (SG) of the spinal cord processes incoming painful information to ascending projection neurons. Whole-cell patch clamp recordings from SG spinal cord slices documented that in a low Ca(2+) /no Mg(2+) (low X(2+) ) external medium aden... |
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Inhibitory coupling between inhibitory interneurons in the spinal cord dorsal horn.
Mol. Pain 5 , 24, (2009) Local inhibitory interneurons in the dorsal horn play an important role in the control of excitability at the segmental level and thus determine how nociceptive information is relayed to higher structures. Regulation of inhibitory interneuron activity may the... |
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Sumatriptan inhibits synaptic transmission in the rat midbrain periaqueductal grey.
Mol. Pain 4 , 54, (2008) There is evidence to suggest that the midbrain periaqueductal grey (PAG) has a role in migraine and the actions of the anti-migraine drug sumatriptan. In the present study we examined the serotonergic modulation of GABAergic and glutamatergic synaptic transmi... |