oxycodone hydrochloride
oxycodone hydrochloride structure
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Common Name | oxycodone hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 124-90-3 | Molecular Weight | 351.825 | |
| Density | 1.39g/cm3 | Boiling Point | 501.6ºC at 760 mmHg | |
| Molecular Formula | C18H22ClNO4 | Melting Point | 261-263ºC | |
| MSDS | Chinese USA | Flash Point | 257.1ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Chem. Res. Toxicol. 23 , 171-83, (2010) Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental drug discovery projects toward safer medicines. In this st... |
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Effect of the norepinephrine transporter (NET) inhibition on μ-opioid receptor (MOR)-induced anti-nociception in a bone cancer pain model.
J. Pharmacol. Sci. 125(3) , 264-73, (2014) Although norepinephrine transporter (NET) inhibition has an additional effect on μ-opioid receptor (MOR)-mediated anti-nociception in inflammatory and neuropathic pain, its effect on cancer pain is not well characterized. We investigated the additional effect... |
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The contribution of Gi/o protein to opioid antinociception in an oxaliplatin-induced neuropathy rat model.
J. Pharmacol. Sci. 126(3) , 264-73, (2014) Oxaliplatin is a chemotherapeutic agent that induces chronic refractory neuropathy. To determine whether opioids effectively relieve this chronic neuropathy, we investigated the efficacies of morphine, oxycodone, and fentanyl, and the mechanisms underlying op... |
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Inhibition of TRPM8 channels reduces pain in the cold pressor test in humans.
J. Pharmacol. Exp. Ther. 351(2) , 259-69, (2014) The transient receptor potential (subfamily M, member 8; TRPM8) is a nonselective cation channel localized in primary sensory neurons, and is a candidate for cold thermosensing, mediation of cold pain, and bladder overactivity. Studies with TRPM8 knockout mic... |
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Spontaneous resolution of quadrilateral space syndrome: a case report.
Am. J. Phys. Med. Rehabil. 94(1) , e1-5, (2015) A case of quadrilateral space syndrome is presented, where a large near-circumferential glenoid labrum tear led to a paralabral cyst that dissected into the quadrilateral space and caused a compressive neuropathy of the axillary nerve. This led to a 6-mo hist... |
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Rational prescribing.
Minn. Med. 96(3) , 4, (2013)
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Extended-release oxycodone and acetaminophen (Xartemis XR).
Med. Lett. Drugs Ther. 56(1447) , 59-60, (2014)
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Opioid prescribing patterns after Mohs micrographic surgery and standard excision: a survey of American Society for Dermatologic Surgery members and a chart review at a single institution.
Dermatol. Surg. 40(8) , 906-11, (2014) Little is known about postoperative opioid prescribing patterns among dermatologic surgeons.To better understand postoperative opioid prescribing patterns among dermatologic surgeons in the United States.Two-part analysis consisting of a retrospective chart r... |
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Pre-emptive analgesia with pregabalin and celecoxib decreases postsurgical pain following maxillomandibular advancement surgery: a randomized controlled clinical trial.
J. Oral Maxillofac. Surg. 72(10) , 1909-14, (2014) The purpose of this study was to determine the efficacy of pre-emptive analgesia with pregabalin and celecoxib on narcotic consumption and perceived pain in adult patients undergoing maxillomandibular advancement surgery for obstructive sleep apnea.This was a... |
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Pulsed electromagnetic fields dosing impacts postoperative pain in breast reduction patients.
J. Surg. Res. 193(1) , 504-10, (2014) Pulsed electromagnetic fields (PEMF) reduce postoperative pain and narcotic requirements in breast augmentation, reduction, and reconstruction patients. PEMF enhances both calmodulin-dependent nitric oxide and/or cyclic guanosine monophosphate signaling and p... |