Gastrin I (human)
Gastrin I (human) structure
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Common Name | Gastrin I (human) | ||
|---|---|---|---|---|
| CAS Number | 10047-33-3 | Molecular Weight | 2098.203 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 2401.4±65.0 °C at 760 mmHg | |
| Molecular Formula | C97H124N20O31S | Melting Point | N/A | |
| MSDS | USA | Flash Point | 1406.1±34.3 °C | |
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In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.
Nature 494 , 247-50, (2013) The Wnt target gene Lgr5 (leucine-rich-repeat-containing G-protein-coupled receptor 5) marks actively dividing stem cells in Wnt-driven, self-renewing tissues such as small intestine and colon, stomach and hair follicles. A three-dimensional culture system al... |
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Human gastrin: a Helicobacter pylori--specific growth factor.
Gastroenterology 117 , 1113-1118, (1999) Helicobacter pylori resides within the gastric mucosa, a niche hostile to other microorganisms. Human gastrin levels are elevated after infection and return to normal after eradication. The aim of this study was to test the direct effect of gastrin on the gro... |
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Evidence for a functional role of the cholecystokinin-B/gastrin receptor in the human fetal and adult pancreas.
Diabetes 48 , 2015-2021, (1999) Gastrin (G) and cholecystokinin (CCK) are gastrointestinal neuropeptides that are released into circulation during a meal. G is also transiently expressed during embryogenic and early ontogenic development of the pancreas and is believed to act on islet-cell ... |
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A comparison of the therapeutic effectiveness of gastrin neutralisation in two human gastric cancer models: relation to endocrine and autocrine/paracrine gastrin mediated growth.
Gut 45 , 812-817, (1999) Gastrin is a growth factor for established tumours.To investigate the therapeutic effect of antibodies, raised against the Gastrimmune immunogen, which neutralise the glycine extended and carboxy amidated forms of gastrin 17 in two human gastric cancer models... |
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Gastrin stimulates the growth of gastric pit with less-differentiated features.
Am. J. Physiol. 277 , G773-G784, (1999) Gastrin stimulates the growth of gastric mucosa by increasing mostly its glandular region but is not known to induce the growth of a pit region where its major constituent cells, gastric surface mucous (GSM) cells, turn over rapidly. To investigate the effect... |