6-iodonordihydrocapsaicin

6-iodonordihydrocapsaicin Structure
6-iodonordihydrocapsaicin structure
Common Name 6-iodonordihydrocapsaicin
CAS Number 859171-97-4 Molecular Weight 419.29800
Density 1.375g/cm3 Boiling Point 552.9ºC at 760 mmHg
Molecular Formula C17H26INO3 Melting Point N/A
MSDS Chinese USA Flash Point 288.2ºC
Symbol GHS07
GHS07
Signal Word Warning

The TRPV1 channel in rodents is a major target for antinociceptive effect of the probiotic Lactobacillus reuteri DSM 17938.

J. Physiol. 593 , 3943-57, (2015)

Certain probiotic bacteria have been shown to reduce distension-dependent gut pain, but the mechanisms involved remain obscure. Live luminal Lactobacillus reuteri (DSM 17938) and its conditioned medium dose dependently reduced jejunal spinal nerve firing evok...

Anxiogenic-like effects induced by hemopressin in rats.

Pharmacol. Biochem. Behav. 129 , 7-13, (2015)

Hemopressin (PVNFKFLSH; HP) is an orally active peptide derived from rat hemoglobin α-chain that could act as an inverse agonist at cannabinoid type 1 receptors (CB1). Here, we aim to investigate possible behavioral effects of HP in male Wistar rats tested in...

Halogenation of a capsaicin analogue leads to novel vanilloid TRPV1 receptor antagonists.

Br. J. Pharmacol. 139 , 1417-1424, (2003)

1. The C-5 halogenation of the vanillyl moiety of resiniferatoxin, an ultrapotent agonist of vanilloid TRPV1 receptors, results in a potent antagonist for these receptors. Here, we have synthesized a series of halogenated derivatives of 'synthetic capsaicin' ...