4-chloro-2-(trichloromethyl)quinoline
4-chloro-2-(trichloromethyl)quinoline structure
|
Common Name | 4-chloro-2-(trichloromethyl)quinoline | ||
|---|---|---|---|---|
| CAS Number | 35871-17-1 | Molecular Weight | 280.96500 | |
| Density | 1.56g/cm3 | Boiling Point | 331.9ºC at 760 mmHg | |
| Molecular Formula | C10H5Cl4N | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 184.7ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
|
Aberrant connexin26 hemichannels underlying keratitis-ichthyosis-deafness syndrome are potently inhibited by mefloquine.
J. Invest. Dermatol. 135(4) , 1033-42, (2015) Keratitis-ichthyosis-deafness (KID) syndrome is an ectodermal dysplasia caused by dominant mutations of connexin26 (Cx26). Loss of Cx26 function causes nonsyndromic sensorineural deafness, without consequence in the epidermis. Functional analyses have reveale... |
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