Isopropyl isocyanide
Isopropyl isocyanide structure
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Common Name | Isopropyl isocyanide | ||
|---|---|---|---|---|
| CAS Number | 598-45-8 | Molecular Weight | 69.10510 | |
| Density | 0.733 g/mL at 25ºC(lit.) | Boiling Point | 75ºC(lit.) | |
| Molecular Formula | C4H7N | Melting Point | N/A | |
| MSDS | Chinese | Flash Point | 69 °F | |
| Symbol |
GHS02, GHS06 |
Signal Word | Danger | |
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Isocyanides inhibit human heme oxygenases at the verdoheme stage.
Biochemistry 48(37) , 8920-8, (2009) Heme oxygenases (HO) catalyze the oxidative cleavage of heme to generate biliverdin, CO, and free iron. In humans, heme oxygenase-1 (hHO-1) is overexpressed in tumor tissues, where it helps to protect cancer cells from anticancer agents, while HOs in fungal p... |
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The reaction of trout hemoglobins with isocyanides.
Eur. J. Biochem. 135(1) , 171-4, (1983) Binding of alkylisocyanides of different bulkiness to the two major components of trout hemolysate is presented. In the case of trout hemoglobin I isocyanide binding is pH-independent, similar to O2 and CO, and the bulkiness of the ligand is related to the en... |
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Isocyanide binding to the copper(I) centers of the catalytic core of peptidylglycine monooxygenase (PHMcc).
J. Biol. Inorg. Chem. 6(5-6) , 567-77, (2001) Binding of the Cu(I)-specific ligands 2,6-dimethylphenyl isocyanide (DIMPI) and isopropyl isocyanide (IPI) to the reduced form of peptidylglycine monooxygenase (PHM) is reported. Both ligands bind to the methionine-containing CuM center, eliciting FTIR bands ... |