4-(Trifluoromethyl)benzoic acid
4-(Trifluoromethyl)benzoic acid structure
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Common Name | 4-(Trifluoromethyl)benzoic acid | ||
|---|---|---|---|---|
| CAS Number | 455-24-3 | Molecular Weight | 190.12 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 243.2±40.0 °C at 760 mmHg | |
| Molecular Formula | C8H5F3O2 | Melting Point | 219-220 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 100.9±27.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Bacterial metabolism of side chain fluorinated aromatics: cometabolism of 4-trifluoromethyl(TFM)-benzoate by 4-isopropylbenzoate grown Pseudomonas putida JT strains.
Arch. Microbiol. 149(3) , 198-206, (1988) Enzymes of the p-cymene pathway in Pseudomonas putida strains cometabolized the intermediate analogue 4-trifluoromethyl(TFM)benzoate. Three products, 4-TFM-2,3-dihydro-2,3-dihydroxybenzoate, 4-TFM-2,3-dihydroxybenzoate and 2-hydroxy-6-oxo-7,7,7-trifluorohepta... |
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Studies on the metabolism of fluorinated xenobiotics in the rat using 19F-NMR and 1H-NMR spectroscopy.
J. Pharm. Biomed. Anal. 8(8-12) , 939-44, (1990)
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Determination of the equilibrium distibution between alcohol and aldehyde substrates when bound to horse liver alcohol dehydrogenase using magnetic resonance.
Biochemistry 19(24) , 5486-93, (1980) The interactions of horse liver alcohol dehydrogenase (LADH) with the rho-trifluoromethyl derivatives of benzyl alcohol, benzaldehyde, and benzoic acid have been investigated by use of 19F nuclear magnetic resonance. The aldehyde and alcohol are good substrat... |
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Antifungal Activity of Salicylanilides and Their Esters with 4-(Trifluoromethyl)benzoic Acid.
Molecules 17(8) , 9426-42, (2012) Searching for novel antimicrobial agents still represents a current topic in medicinal chemistry. In this study, the synthesis and analytical data of eighteen salicylanilide esters with 4-(trifluoromethyl)benzoic acid are presented. They were assayed in vitro... |
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Total synthesis of the C-1027 chromophore core: extremely facile enediyne formation through Sml2-mediated 1,2-elimination.
Angew. Chem. Int. Ed. Engl. 47(9) , 1777-9, (2008)
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High resolution magic angle spinning NMR to investigate ligand-receptor binding events for mass-limited samples in liquids.
J. Pharm. Biomed. Anal. 59 , 13-7, (2012) This work shows that high resolution magic angle spinning (HR-MAS) can be used to elucidate ligand-receptor binding phenomena for mass-limited samples in liquid solution. With respect to conventional 5mm liquid-state NMR probe heads, HR-MAS allows for a consi... |
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Ultra trace determination of fluorinated aromatic carboxylic acids in aqueous reservoir fluids by solid phase extraction in combination with negative ion chemical ionisation mass spectrometry after derivatisation with pentafluorobenzyl bromide. Galdiga CU and Greibrokk T.
Fresenius J. Anal. Chem. 361(8) , 797-802, (1998)
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