Resorufin pentyl ether

Resorufin pentyl ether Structure
Resorufin pentyl ether structure
Common Name Resorufin pentyl ether
CAS Number 87687-03-4 Molecular Weight 283.32200
Density 1.2g/cm3 Boiling Point 423.6ºC at 760 mmHg
Molecular Formula C17H17NO3 Melting Point 151-153ºC
MSDS Chinese USA Flash Point 183.4ºC
Symbol GHS07
GHS07
Signal Word Warning

Effect of commercially available green and black tea beverages on drug-metabolizing enzymes and oxidative stress in Wistar rats.

Food Chem. Toxicol. 70 , 120-7, (2014)

The effect of commercially available green tea (GT) and black tea (BT) drinks on drug metabolizing enzymes (DME) and oxidative stress in rats was investigated. Male Wistar rats were fed a laboratory chow diet and GT or BT drink for 5 weeks. Control rats recei...

In vivo indirect measurement of cytochrome P450-associated activities in freshwater gastropod molluscs.

Environ. Toxicol. 25(6) , 545-53, (2010)

The cytochrome P450 (CYP) system is widely distributed across phyla and plays a key role in the metabolism of xenobiotic compounds. However, most studies on CYP system were developed on vertebrates and among invertebrates, gastropod molluscs are rarely used. ...

Effects of age increase on hepatic expression and activity of cytochrome P450 in male C57BL/6 mice.

Arch. Pharm. Res. 38 , 857-64, (2015)

Effects of aging on hepatic expression and activity of cytochrome P450 (CYP) isoforms were investigated in male mice aged 2, 6, 18, and 30 months. Microsomal protein, total CYP, cytochrome b5 and NADPH-dependent cytochrome P450 reductase contents in liver wer...

Biotransformation and Oxidative Stress Responses in Captive Nile Crocodile (Crocodylus niloticus) Exposed to Organic Contaminants from the Natural Environment in South Africa.

PLoS ONE 10 , e0130002, (2015)

In the present study, the biotransformation and oxidative stress responses in relation to chemical burden in the liver of male and female Nile crocodiles--Crocodylus niloticus--from a commercial crocodile farm passively exposed to various anthropogenic aquati...

Transplantation of human adipose stem cell-derived hepatocyte-like cells with restricted localization to liver using acellular amniotic membrane.

Stem Cell Res. Ther. 6 , 217, (2015)

Adult stem cell-derived hepatocytes transplantation holds considerable promise for future clinical individualized therapy of liver failure or dysfunction. However, the low engraftment of the available hepatocytes in the liver disease microenvironment has been...

Selective induction of hepatic cytochrome P450 2B activity by leelamine in vivo, as a potent novel inducer.

Arch. Pharm. Res. 38 , 725-33, (2015)

Cytochrome P450 (CYP) is an important enzyme that can act on xenobiotic substances such as toxic chemicals or drugs. Phenobarbital (PB) has been widely used to induce CYP2B activity to investigate the drug-drug interaction of CYP2B substrate drugs. Leelamine ...

Influence of dietary macronutrients on induction of hepatic drug metabolizing enzymes by Coleus forskohlii extract in mice.

J. Nutr. Sci. Vitaminol. 59(1) , 37-44, (2013)

From studies in mice, we have reported that Coleus forskohlii extract (CFE), a popular herbal weight-loss ingredient, markedly induced hepatic drug metabolizing enzymes, especially cytochrome P450 (CYP), and interacted with co-administered drugs. This study w...

Precision-cut liver slices from rats of different ages: basal cytochrome P450-dependent monooxygenase activities and inducibility.

Anal. Bioanal. Chem 392(6) , 1173-84, (2008)

The biotransformation capacity - of the cytochrome P450 (CYP) system for example - is lower but inducibility is more pronounced in neonates than in adults. On the other hand, both enzyme activities and inducibility decline with senescence. Precision-cut rat l...

Raphanus sativus cv. Sango Sprout Juice Decreases Diet-Induced Obesity in Sprague Dawley Rats and Ameliorates Related Disorders.

PLoS ONE 11 , e0150913, (2016)

Obesity is recognized as a leading global health problem, correlated with an increased risk for several chronic diseases. One strategy for weight control management includes the use of vegetables rich in bioactive compounds to counteract weight gain, improve ...

Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450.

Biochem. Pharmacol. 34 , 3337, (1985)

The individual members of a homologous series of phenoxazone ethers related to ethoxyresorufin were O-dealkylated, and the parent compound phenoxazone was ring-hydroxylated, each at different rates with hepatic microsomes of untreated rats. A structure-activi...