2,2'-Methylenebis(6-tert-butyl-4-ethylphenol)

2,2'-Methylenebis(6-tert-butyl-4-ethylphenol) Structure
2,2'-Methylenebis(6-tert-butyl-4-ethylphenol) structure
Common Name 2,2'-Methylenebis(6-tert-butyl-4-ethylphenol)
CAS Number 88-24-4 Molecular Weight 368.552
Density 1.0±0.1 g/cm3 Boiling Point 452.1±40.0 °C at 760 mmHg
Molecular Formula C25H36O2 Melting Point 119-122 °C(lit.)
MSDS Chinese USA Flash Point 187.5±21.9 °C
Symbol GHS07
GHS07
Signal Word Warning

Toxicity studies of a synthetic antioxidant, 2,2'-methylenebis (4-ethyl-6-tert-butylphenol) in rats. 2. Uncoupling effect on oxidative phosphorylation of liver mitochondria.

J. Toxicol. Sci. 18(1) , 49-55, (1993)

Effects of 2,2'-methylenebis (4-ethyl-6-tert-butylphenol) (MBEBP) on hepatic mitochondrial oxidative phosphorylation in vitro, and on hepatic peroxisomal enzymes activities and microsomal mixed-function oxidase activities were studied. 1. A low concentration ...

[Distribution of 2,2'-methylenebis (4-ethyl-6-tert-butylphenol) in rat tissues].

Eisei Shikenjo Hokoku. (105) , 26-8, (1987)

[Distribution of 2,2'-methylenebis (4-ethyl-6-tert-butylphenol) in rat fat].

Eisei Shikenjo Hokoku. (106) , 105-6, (1988)

[Studies on the teratogenic potential of 2,2'-methylenebis (4-ethyl-6-tert-buthylphenol) in rats].

Eisei Shikenjo Hokoku. (107) , 51-5, (1989)

2,2'-Methylenebis (4-ethyl-6-tert-buthylphenol), an antioxidant, was given orally to pregnant Wistar rats by stomach intubation at the dose levels of 187, 375 or 750 mg/kg body weight during days 7 to 17 of gestation, and the effects of the compound on dams a...

Toxicity studies of a synthetic antioxidant, 2,2'-methylenebis (4-ethyl-6-tert-butylphenol) in rats. 1. Acute and subchronic toxicity.

J. Toxicol. Sci. 17(3) , 135-53, (1992)

The acute and subchronic toxicity studies on 2,2'-methylenebis (4-ethyl-6-tert-butylphenol) (MBEBP) were conducted using male and female Wistar rats. In acute toxicity test, the LD50 values were estimated to be greater than 10 g/kg BW by oral and intraperiton...

Effects of four bisphenolic antioxidants on lipid contents of rat liver.

Toxicol. Lett. 8(1-2) , 77-86, (1981)

Hepatic lipids were studied in Sprague-Dawley male rats given, 2,2'-methylenebis(4-ethyl-6-tert-butylphenol), 2,2'-methylenebis(4-methyl-6-tert-butylphenol), 4,4'-butylidenebis(3-methyl-6-tert-butylphenol) or 4,4'-methylenebis(2,6-di-tert-butylphenol) at a le...

Chronic oral toxicity of a synthetic antioxidant, 2,2'-methylenebis(4-ethyl- 6-tert-butylphenol), in rats.

J. Appl. Toxicol. 16(1) , 15-23, (1996)

Groups of 30 Wistar rats of each sex were treated with 2,2'-methylenebis(4-ethyl-6-tert-butylphenol) (MBEBP) in the diet at levels of 0, 0.03, 0.1 and 0.3% for up to 18 months. In both sexes, survival rates of treated groups were similar to those of the contr...