3,4-Dibenzyloxyphenethylamine hydrochloride
3,4-Dibenzyloxyphenethylamine hydrochloride structure
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Common Name | 3,4-Dibenzyloxyphenethylamine hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 1699-56-5 | Molecular Weight | 369.88400 | |
| Density | 1.128g/cm3 | Boiling Point | 493.4ºC at 760 mmHg | |
| Molecular Formula | C22H24ClNO2 | Melting Point | 131-133ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 279.8ºC | |
| Symbol |
GHS05, GHS07, GHS09 |
Signal Word | Danger | |
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Design, synthesis and brain uptake of LAT1-targeted amino acid prodrugs of dopamine.
Pharm. Res. 30(10) , 2523-37, (2013) Drug delivery to the brain is impeded by the blood-brain barrier (BBB). Here, we attempted to enhance the brain uptake of cationic dopamine by utilizing the large amino acid transporter 1 (LAT1) at the BBB by prodrug approach.Three amino acid prodrugs of dopa... |
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Tetrahydroisoquinoline derivatives containing a benzenesulfonamide moiety as potent, selective human beta3 adrenergic receptor agonists.
Bioorg. Med. Chem. Lett. 10(20) , 2283-6, (2000) Tetrahydroisoquinoline derivatives containing a 4-(hexylureido)benzenesulfonamide were examined as human beta3 adrenergic receptor (AR) agonists. Notably, 4,4-biphenyl derivative 9 was a 6 nM full agonist of the beta3 AR. Naphthyloxy compound 18 (beta3 EC50 =... |
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