H-Lys-OMe.2HCl

H-Lys-OMe.2HCl Structure
H-Lys-OMe.2HCl structure
Common Name H-Lys-OMe.2HCl
CAS Number 26348-70-9 Molecular Weight 233.136
Density 1.031g/cm3 Boiling Point 243.9ºC at 760mmHg
Molecular Formula C7H18Cl2N2O2 Melting Point 213-215°C
MSDS Chinese USA Flash Point 93.5ºC

pH-responsive, lysine-based hydrogels for the oral delivery of a wide size range of molecules.

Int. J. Pharm. 478(2) , 496-503, (2015)

Hydrogels synthesized from poly(l-lysine isophthalamide) (PLP) crosslinked with l-lysine methyl ester were investigated as drug delivery systems for a wide size range of molecules (0.3-2000kDa). PLP is an anionic, pseudo-peptidic polymer that is an ideal hydr...

A neutral polydisulfide containing Gd(III) DOTA monoamide as a redox-sensitive biodegradable macromolecular MRI contrast agent.

Contrast Media Mol. Imaging 11 , 32-40, (2016)

This work aims to develop safe and effective gadolinium (III)-based biodegradable macromolecular MRI contrast agents for blood pool and cancer imaging. A neutral polydisulfide containing macrocyclic Gd-DOTA monoamide (GOLS) was synthesized and characterized. ...

Characterization of the chemical degradation of hyaluronic acid during chemical gelation in the presence of different cross-linker agents.

Carbohydr. Res. 342 , 2776-2792, (2007)

Dynamic light scattering (DLS) and rheological experiments have been performed on semidilute aqueous hyaluronic acid (HA) solutions during the chemical cross-linking process with a water-soluble carbodiimide (WSC) to produce a hydrogel. The formation and dest...

Lysine-bisglycidol conjugates as novel lysine cationic surfactants.

Langmuir 25 , 7803-7814, (2009)

The synthesis of a novel class of lysine-based cationic amphiphilic derivatives of the type N(epsilon),N(epsilon)'-bis(n-acyloxypropyl)-l-lysine methyl ester salts combining several hydroxyl functions and aliphatic chains of 12 or 14 carbon atoms is described...

Synthesis, physical and biological properties of lithocholyl-lysyl-fluorescein: a fluorescent monohydroxy bile salt analogue with cholestatic properties.

Biochim. Biophys. Acta 1336 , 485-496, (1997)

We have synthesised and characterised a fluorescent monohydroxy bile salt analogue, lithocholyl-lysyl-fluorescein and compared its physical and biological properties with those of lithocholate, glycolithocholate, sulpholithocholate, lithocholic acid glucuroni...