L-Citruline
L-Citruline structure
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Common Name | L-Citruline | ||
|---|---|---|---|---|
| CAS Number | 372-75-8 | Molecular Weight | 175.186 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 386.7±42.0 °C at 760 mmHg | |
| Molecular Formula | C6H13N3O3 | Melting Point | 214 °C | |
| MSDS | Chinese USA | Flash Point | 187.7±27.9 °C | |
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Development of High-purity Certified Reference Materials for 17 Proteinogenic Amino Acids by Traceable Titration Methods.
Anal. Sci. 31 , 805-14, (2015) To ensure the reliability of amino acid analyses, the National Metrology Institute of Japan of the National Institute of Advanced Industrial Science and Technology (NMIJ/AIST) has developed high-purity certified reference materials (CRMs) for 17 proteinogenic... |
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Down regulation of NO signaling in Trypanosoma cruzi upon parasite-extracellular matrix interaction: changes in protein modification by nitrosylation and nitration.
PLoS Negl. Trop. Dis. 9 , e0003683, (2015) Adhesion of the Trypanosoma cruzi trypomastigotes, the causative agent of Chagas' disease in humans, to components of the extracellular matrix (ECM) is an important step in host cell invasion. The signaling events triggered in the parasite upon binding to ECM... |
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Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.
Nature 457(7231) , 910-4, (2009) Multiple, complex molecular events characterize cancer development and progression. Deciphering the molecular networks that distinguish organ-confined disease from metastatic disease may lead to the identification of critical biomarkers for cancer invasion an... |
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Urinary and plasma organic acids and amino acids in chronic fatigue syndrome.
Clin. Chim. Acta 361(1-2) , 150-8, (2005) Previous work by others have suggested the occurrence of one or more chemical or metabolic 'markers' for ME/CFS including specific amino acids and organic acids and a number of unidentified compounds (CFSUM1, CFSUM2). We have shown elsewhere that CFSUM1 is pa... |
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[Ureido-¹⁵N]citrulline UPLC-MS/MS nitric oxide synthase (NOS) activity assay: development, validation, and applications to assess NOS uncoupling and human platelets NOS activity.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 965 , 173-82, (2014) In healthy human subjects, less than 0.2% of l-arginine is converted to l-citrulline and nitric oxide (NO) by NO synthases (NOS), a metabolic pathway present in all cell types. Assessment of NOS activity in vitro and in vivo by measuring l-citrulline or NO is... |
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Identification and quantitation of biomarkers for radiation-induced injury via mass spectrometry.
Health Phys. 106(1) , 106-19, (2014) Biomarker identification and validation for radiation exposure is a rapidly expanding field encompassing the need for well defined animal models and advanced analytical techniques. The resources within the consortium, Medical Countermeasures Against Radiologi... |
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Development and validation of a LC-MS/MS assay for quantitation of plasma citrulline for application to animal models of the acute radiation syndrome across multiple species.
Anal. Bioanal. Chem 406(19) , 4663-75, (2014) The potential risk of a radiological catastrophe highlights the need for identifying and validating potential biomarkers that accurately predict radiation-induced organ damage. A key target organ that is acutely sensitive to the effects of irradiation is the ... |
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Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease.
J. Neurosci. 35(15) , 5969-82, (2015) The pathogenesis of Alzheimer's disease (AD) is a critical unsolved question; and although recent studies have demonstrated a strong association between altered brain immune responses and disease progression, the mechanistic cause of neuronal dysfunction and ... |
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Digital plethysmography and arginine metabolism in prehypertension: effect of nebivolol therapy.
J. Clin. Hypertens. (Greenwich.) 17(1) , 14-9, (2015) Prehypertension is an important phenotype for cardiovascular risk and development of established hypertension. To better understand the early circulatory changes in this group, the authors studied 34 patients with prehypertension (blood pressure 120-139/80-89... |
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Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.
Nat. Chem. Biol. 5 , 45-52, (2009) Transporter-related nutrient sensors, called transceptors, mediate nutrient activation of signaling pathways through the plasma membrane. The mechanism of action of transporting and nontransporting transceptors is unknown. We have screened 319 amino acid anal... |