(2S)-2-Amino-4-pentenoic acid
(2S)-2-Amino-4-pentenoic acid structure
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Common Name | (2S)-2-Amino-4-pentenoic acid | ||
|---|---|---|---|---|
| CAS Number | 16338-48-0 | Molecular Weight | 115.131 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 222.7±23.0 °C at 760 mmHg | |
| Molecular Formula | C5H9NO2 | Melting Point | 283 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 88.5±22.6 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ... |
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Effects of chronic inhibition of GABA synthesis on attention and impulse control.
Pharmacol. Biochem. Behav. 135 , 97-104, (2015) Cortical GABA regulates a number of cognitive functions including attention and working memory and is dysregulated in a number of psychiatric conditions. In schizophrenia for example, changes in GABA neurons [reduced expression of glutamic acid decarboxylase ... |
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Antidepressant and anxiolytic profiles of newly synthesized arginine vasopressin V1B receptor antagonists: TASP0233278 and TASP0390325.
Br. J. Pharmacol. , doi:10.1111/bph.12699, (2014) Vasopressin V1B receptor antagonists may be effective for the treatment of depression and anxiety and the objective of this study was to characterize the pharmacological profiles of two newly synthesized arginine vasopressin receptor 1B (V1B receptor) antagon... |
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In vivo modulation of benzodiazepine receptor function after inhibition of endogenous gamma-aminobutyyric acid synthesis.
Eur. J. Pharmacol. 321 , 13, (1997) The influence of decreased endogenous gamma-aminobutyric acid (GABA) concentration on benzodiazepine receptor function was studied in the brain of living baboons. Positron emission tomography and the radiotracer [11C]flumazenil combined with electroencephalog... |
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Injection of L-allylglycine into the posterior hypothalamus in rats causes decreases in local GABA which correlate with increases in heart rate.
Neuropharmacology 27 , 1171-1177, (1988) Injection of the GABA antagonist, bicuculline methiodide into the posterior hypothalamus of rats has been shown to cause marked increases in heart rate and lesser elevations in blood pressure. Allylglycine is a potent inhibitor of the synthetic enzyme for GAB... |
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Allylglycine-induced seizures in male and female rats.
Physiol. Behav. 49 , 1181-1183, (1991) The possibility that a sex difference in gamma-aminobutyric acid (GABA) activity might be an underlying cause of the previously reported sex differences in picrotoxin-induced seizures was investigated. Male and female rats were injected (IP) with the GABA ant... |