Xanthone
Xanthone structure
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Common Name | Xanthone | ||
|---|---|---|---|---|
| CAS Number | 90-47-1 | Molecular Weight | 196.201 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 350.0±12.0 °C at 760 mmHg | |
| Molecular Formula | C13H8O2 | Melting Point | 172-174 °C(lit.) | |
| MSDS | USA | Flash Point | 169.8±13.1 °C | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Synergistic Effects Between Thioxanthones and Oxacillin Against Methicillin-Resistant Staphylococcus aureus.
Microb. Drug Resist. 21 , 404-15, (2015) The extensive use of antimicrobials is leaving medicine with few effective therapeutic options to treat many infections due to the fact that many organisms developed resistance to commonly used drugs. It is therefore pertinent to search not only for new antim... |
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Xanthones from roots, hairy roots and cell suspension cultures of selected Hypericum species and their antifungal activity against Candida albicans.
Plant Cell Rep. 34 , 1953-62, (2015) Highest xanthone contents were found in Hypericum pulchrum and H. annulatum untransformed roots. The best anti- Candida activity was obtained for hairy roots extracts of H. tetrapterum clone 2 ATCC 15834. Extracts of root cultures, hairy roots and cell suspen... |
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Identification and characterization of mefloquine efficacy against JC virus in vitro.
Antimicrob. Agents Chemother. 53 , 1840-9, (2009) Progressive multifocal leukoencephalopathy (PML) is a rare but frequently fatal disease caused by the uncontrolled replication of JC virus (JCV), a polyomavirus, in the brains of some immunocompromised individuals. Currently, no effective antiviral treatment ... |
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Effects of glucose on cell viability and antioxidant and anti-inflammatory properties of phytochemicals and phytochemically modified membranes.
J. Phys. Chem. B 118(41) , 11993-2001, (2014) By virtue of antioxidant and anti-inflammable properties, plant-derived phytochemicals such as mangiferin and genistein have attracted considerable attention for functionalization of polymeric hemodialysis (HD) membranes via solution blending. In-vitro dihydr... |
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Development of noncytotoxic PLGA nanoparticles to improve the effect of a new inhibitor of p53-MDM2 interaction.
Int. J. Pharm. 454(1) , 394-402, (2013) One possible approach to overcome solubility complications and enhance the biological activity of drugs is their incorporation into drug delivery systems. Within this scope, several nanosphere and nanocapsule formulations of a new inhibitor of p53-MDM2 intera... |
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[Chemical constituents from cell suspension cultures of Cudrania tricuspidata].
Zhongguo Zhong Yao Za Zhi 37(24) , 3734-7, (2012) Ten compounds were isolated and purified from cell suspension cultures of Cudrania tricuspidata with silica-gel column chromatography, semi-preparative HPLC and Sephadex LH-20. On the base of their physicochemical properties and spectral data, their structure... |
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Mangiferin, a natural xanthone, protects murine liver in Pb(II) induced hepatic damage and cell death via MAP kinase, NF-κB and mitochondria dependent pathways.
PLoS ONE 8(2) , e56894, (2013) One of the most well-known naturally occurring environmental heavy metals, lead (Pb) has been reported to cause liver injury and cellular apoptosis by disturbing the prooxidant-antioxidant balance via oxidative stress. Several studies, on the other hand, repo... |
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Cyclopia maculata and Cyclopia subternata (honeybush tea) inhibits adipogenesis in 3T3-L1 pre-adipocytes.
Phytomedicine 20(5) , 401-8, (2013) The stems, leaves and flowers of Cyclopia have been consumed as a herbal tea 'honeybush tea' to treat various medical ailments since the 19th century. Plant polyphenols are reported to inhibit adipogenesis in cell and animal models of obesity. The aim of this... |
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Anticonvulsant evaluation of aminoalkanol derivatives of 2- and 4-methylxanthone.
Bioorg. Med. Chem. 21(5) , 1190-8, (2013) A series of 17 new aminoalkanol derivatives of 6-methoxy- or 7-chloro-2-methylxanthone as well as 6-methoxy-4-methylxanthone was synthesized and evaluated for anticonvulsant activity. All compounds were verified in mice after intraperitoneal (ip) administrati... |
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Benzophenones and xanthones fromGarcinia cantleyanavar.cantleyanaand their inhibitory activities on human low-density lipoprotein oxidation and platelet aggregation
Phytochemistry 80 , 58-63, (2012) Graphical abstract Four benzophenones and five xanthones isolated from the twigs of Garcinia cantleyana var. cantleyana showed high LDL antioxidant and antiplatelet activities with one xanthone exhibiting the strongest inhibition on LDL oxidation with IC50 va... |