Trimethyloxonium tetrafluoroborate

Trimethyloxonium tetrafluoroborate Structure
Trimethyloxonium tetrafluoroborate structure
Common Name Trimethyloxonium tetrafluoroborate
CAS Number 420-37-1 Molecular Weight 147.908
Density N/A Boiling Point N/A
Molecular Formula C3H9BF4O Melting Point 200 °C
MSDS Chinese USA Flash Point N/A
Symbol GHS05
GHS05
Signal Word Danger

Toward the total synthesis of spirastrellolide A. Part 2: Conquest of the northern hemisphere.

Angew. Chem. Int. Ed. Engl. 45 , 5510, (2006)

Profiling of organic acids by capillary gas chromatography-mass spectrometry after direct methylation in urine using trimethyloxonium tetrafluoroborate.

J. Chromatogr. A. 843(1-2) , 237-45, (1999)

Trimethyloxonium tetrafluoroborate (TMO) is applied as derivatising reagent to transform urinary organic acids into their methyl esters. The method is suggested as an alternative to the use of diazomethane which is carcinogenic and explosive. In contrast to o...

Urinary organic acid screening by solid-phase microextraction of the methyl esters.

J. Chromatogr. B. Biomed. Sci. Appl. 713(2) , 427-32, (1998)

We developed a new sample preparation method for profiling organic acids in urine by GC or GC-MS. The method includes derivatisation of the organic acids directly in the aqueous urine using trimethyloxonium tetrafluoroborate as a methylating agent, extraction...

Determination of organic acids in urine by solid-phase microextraction and gas chromatography-ion trap tandem mass spectrometry previous 'in sample' derivatization with trimethyloxonium tetrafluoroborate.

Biomed. Chromatogr. 22(10) , 1155-63, (2008)

A method for the determination of the organic acids directly in the urine employing derivatization with trimethyloxonium tetrafluoroborate as a methylating agent and sequential extraction by head space and direct immersion/solid phase microextraction is repor...

Novel method for simultaneous aqueous in situ derivatization of THC and THC-COOH in human urine samples: validation and application to real samples.

J. Anal. Toxicol. 35(4) , 193-8, (2011)

The present work describes the validation of a novel aqueous in situ derivatization procedure with trimethyloxonium tetrafluoroborate (TMO) as methylating agent for the simultaneous, quantitative analysis of Δ(9)-tetrahydrocannabinol (THC) and 11-nor-Δ(9)-tet...

Modification of carboxyl groups in sea anemone toxin RTX-III from Radianthus macrodactylus.

Toxicon 28(11) , 1255-63, (1990)

The toxin was treated with [14C]trimethyloxonium tetrafluoroborate or [3H]glycine methyl ester in the presence of 1-ethyl-3(3-dimethylaminopropyl) carbodiimide. Esterification of separate carboxyl groups with [14C]trimethyloxonium tetrafluoroborate decreased ...