α-Hydroxytriazolam

α-Hydroxytriazolam Structure
α-Hydroxytriazolam structure
Common Name α-Hydroxytriazolam
CAS Number 37115-45-0 Molecular Weight 359.20900
Density N/A Boiling Point N/A
Molecular Formula C17H12Cl2N4O Melting Point 239-241℃
MSDS Chinese USA Flash Point 9℃
Symbol GHS02 GHS06 GHS08
GHS02, GHS06, GHS08
Signal Word Danger

LC-MS/MS analysis of 13 benzodiazepines and metabolites in urine, serum, plasma, and meconium.

Methods Mol. Biol. 603 , 89-105, (2010)

We describe a single method for the detection and quantitation of 13 commonly prescribed benzodiazepines and metabolites: alpha-hydroxyalprazolam, alpha-hydroxyethylflurazepam, alpha-hydroxytriazolam, alprazolam, desalkylflurazepam, diazepam, lorazepam, midaz...

Quantitation of benzodiazepines in blood and urine using gas chromatography-mass spectrometry (GC-MS).

Methods Mol. Biol. 603 , 75-87, (2010)

The benzodiazepine assay utilizes gas chromatography-mass spectrometry (GC-MS) for the analysis of diazepam, nordiazepam, oxazepam, temazepam, lorazepam, alpha-hydroxyalprazolam, and alpha-hydroxytriazolam in blood and urine. A separate assay is employed for ...

Sensitive UPLC-MS-MS assay for 21 benzodiazepine drugs and metabolites, zolpidem and zopiclone in serum or plasma.

J. Anal. Toxicol. 36(7) , 472-6, (2012)

This paper reports an ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS-MS) method to quantitate 21 benzodiazepines, zolpidem and zopiclone in serum and plasma. After liquid-liquid extraction, an Acquity UPLC with a TQ Detector and BEH...

A drug rape case involving triazolam detected in hair and urine.

Int. J. Legal Med. 126(4) , 637-43, (2012)

In recent years, there has been heightened awareness regarding the use of drugs to modify a person's behavior to facilitate crime. A drug rape case involving the potent, short-acting sedative triazolam will be presented. On three occasions, the victim consume...

Simultaneous quantification of triazolam and its metabolites in human urine by liquid chromatography-tandem mass spectrometry.

J. Anal. Toxicol. 35(3) , 170-5, (2011)

A simple, simultaneous, sensitive and selective liquid chromatography-tandem mass spectrometry (LC-MS-MS) method for the determination of triazolam and its metabolites, α-hydroxytriazolam (α-OHTRZ) and 4-hydroxytriazolam (4-OHTRZ), in human urine was develope...

Acute intoxication caused by overdose of flunitrazepam and triazolam: high concentration of metabolites detected at autopsy examination.

Am. J. Forensic Med. Pathol. 33(4) , 293-6, (2012)

A 52-year-old woman was found dead on the floor of the living room on the first floor of a house, which belonged to the man with whom she shared the house. On visiting the site, her clothes were found to be undisturbed. Packages of flunitrazepam (Silece, 2 mg...

Urinalysis of alpha-hydroxyalprazolam, alpha-hydroxytriazolam, and other benzodiazepine compounds by GC/EIMS.

J. Anal. Toxicol. 16 , 67, (1992)

This procedure was developed as an overall benzodiazepine confirmation scheme and includes the detection of the most important urinary analytes encountered by clinical toxicology laboratories in North America: alpha-hydroxyalprazolam, alpha-hydroxytriazolam, ...

[Determination of alpha-hydroxytrizolam and alpha hydroxyaplrazolam from urine by acetylation derivatization using gas chromatography electron capture detection].

Se Pu 22(6) , 664, (2004)

Determination of triazolam and alpha-hydroxytriazolam in guinea pig hair after a single dose.

J. Anal. Toxicol. 34(2) , 89-94, (2010)

A sensitive liquid chromatography-tandem mass spectrometry method is presented for determination of triazolam and alpha-hydroxytriazolam in guinea pig hair after a single dose of triazolam. Eighteen guinea pigs were divided into three dosage groups (10, 100, ...

Urinary excretion of alpha-hydroxytriazolam following a single dose of halcion.

J. Anal. Toxicol. 29(2) , 118-23, (2005)

As an approved medicinal product and reportedly an abused substance that have been associated with death and "considered to be a factor...of impaired driving, sexual assault, and other violent crimes", triazolam is controlled at the same level (Level III) as ...