Patulin

Patulin Structure
Patulin structure
Common Name Patulin
CAS Number 149-29-1 Molecular Weight 154.120
Density 1.5±0.1 g/cm3 Boiling Point 513.7±50.0 °C at 760 mmHg
Molecular Formula C7H6O4 Melting Point 108-111 °C
MSDS Chinese USA Flash Point 226.8±23.6 °C
Symbol GHS06
GHS06
Signal Word Danger

Molecular characterization, fitness and mycotoxin production of benzimidazole-resistant isolates of Penicillium expansum.

Int. J. Food Microbiol. 162(3) , 237-44, (2013)

Penicillium expansum field-strains resistant to benzimidazole fungicides were isolated in high frequency from decayed apple fruit collected from packinghouses and processing industries located in the region of Imathia, N. Greece. In vitro fungitoxicity tests ...

Changes in poly(A) tail length dynamics from the loss of the circadian deadenylase Nocturnin.

Sci. Rep. 5 , 17059, (2015)

mRNA poly(A) tails are important for mRNA stability and translation, and enzymes that regulate the poly(A) tail length significantly impact protein profiles. There are eleven putative deadenylases in mammals, and it is thought that each targets specific trans...

STIM1 controls T cell-mediated immune regulation and inflammation in chronic infection.

J. Clin. Invest. 125 , 2347-62, (2015)

Chronic infections induce a complex immune response that controls pathogen replication, but also causes pathology due to sustained inflammation. Ca2+ influx mediates T cell function and immunity to infection, and patients with inherited mutations in the gene ...

Auxin Biosynthesis, Accumulation, Action and Transport are Involved in Stress-Induced Microspore Embryogenesis Initiation and Progression in Brassica napus.

Plant Cell Physiol. 56 , 1401-17, (2015)

Isolated microspores are reprogrammed in vitro by stress, becoming totipotent cells and producing embryos and plants via a process known as microspore embryogenesis. Despite the abundance of data on auxin involvement in plant development and embryogenesis, no...

Mold elicits atopic dermatitis by reactive oxygen species: Epidemiology and mechanism studies.

Clin. Immunol. 161 , 384-90, (2015)

Mold has been implicated in the development of atopic dermatitis (AD); however, the underlying mechanisms remain unknown. The aim of the study was to investigate the effects of mold exposure in early life through epidemiologic and mechanistic studies in vivo ...

Metabolic and metagenomic outcomes from early-life pulsed antibiotic treatment.

Nat. Commun. 6 , 7486, (2015)

Mammalian species have co-evolved with intestinal microbial communities that can shape development and adapt to environmental changes, including antibiotic perturbation or nutrient flux. In humans, especially children, microbiota disruption is common, yet the...

Identifying off-target effects and hidden phenotypes of drugs in human cells.

Nat. Chem. Biol. 2 , 329-37, (2006)

We present a strategy for identifying off-target effects and hidden phenotypes of drugs by directly probing biochemical pathways that underlie therapeutic or toxic mechanisms in intact, living cells. High-content protein-fragment complementation assays (PCAs)...

Quantification of patulin in fruit leathers by ultra-high-performance liquid chromatography-photodiode array (UPLC-PDA).

Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 32 , 1164-74, (2015)

Patulin is a mycotoxin commonly found in certain fruit and fruit products. For this reason many countries have established regulatory limits pertaining to, in particular, apple juice and apple products. Fruit leathers are produced by dehydrating fruit puree, ...

Secondary prevention strategy of cardiovascular disease using endothelial function testing.

Circ. J. 79(4) , 685-94, (2015)

Over the past decades, secondary prevention of cardiovascular (CV) disease has improved and considerably reduced mortality rates. However, there remains a high-rate of new or recurrent CV events in those with established atherosclerotic vascular diseases. Alt...

Individual and combined effects of mycotoxins from typical indoor moulds.

Toxicol. In Vitro 27(6) , 1970-8, (2013)

The mycotoxins patulin, gliotoxin and sterigmatocystin can be produced by common indoor moulds and enter the human body via inhalation of mycotoxin containing spores and particulates. There are various studies about the individual effects of these mycotoxins,...